The fixture will afford the Springboks a further opportunity to conditions in Japan, where the team has never previously played.
England coach Eddie Jones said his team needed a change in attitude to turn around Saturday's test against Japan.
Despite trailing at halftime, England found their try-scoring form in the second half to get the better of Japan at Twickenham.
Can Scotland build on their home run against South Africa? And will England's second-string side impress against Japan? ESPN assesses the biggest talking points and players to watch.
Joe Cokanasiga will make his England debut against Japan on Saturday as Eddie Jones made 11 changes to the side that started in the defeat to New Zealand last weekend.
George Kruis has been ruled out England's remaining November fixtures as head coach Eddie Jones named his squad to face Japan this weekend.
Japan head coach Jamie Joseph has revealed his squad are paid just £13 day as they prepare to face England on Saturday.
A fired-up Eddie Jones says his England side will be "absolutely ruthless" and aiming to "physically smash" Japan when the teams meet on Saturday.
ESPN picks the key players and biggest talking points ahead of the opening round of the autumn internationals.
Eddie Jones says he has approached the Football Association for advice before deciding if he will allow players' wives and girlfriends to attend the 2019 Rugby World Cup in Japan.
With Asia's first Rugby World Cup on the horizon, the 12 host cities are preparing themselves for an estimated 400,000 visiting fans from across the world.
The Sunwolves will have a fourth head coach in four Super Rugby seasons after Jamie Joseph announced he'll stand aside in 2019.
In exactly a year's time, World Rugby can say it has grown up. This time next year Japan will turn on one of the great Rugby World Cups, albeit eight years later than it should have, Greg Growden writes.
With one year to go until the Rugby World Cup kicks off in Japan, our writers take a look through each of the pools and decide where it will all be won and lost in 2019.
He's the son of an All Blacks great, yet Michael Little could end up wearing the red and white of Japan as he continues to star for the Sunwolves in Super Rugby. He has a message for those who want to see the franchise's demise, too.
Japan will kick off the 2019 Rugby World Cup in a little under two years. ESPN looks at how the host nation's preparations are going as they shoot for a place in the quarterfinals on home soil.
The Wallabies have their spring tour off to a flyer with a 63-30 romp over Japan in their Test at Yokohama's International Stadium.
In-form utility Reece Hodge will move into the playmaking hot-seat this weekend after he was named to start at No.10 for the Wallabies in the historic clash with Japan.
The Wallabies shouldn't have too much trouble in disposing of Japan despite the Australians being down some key personnel. The bigger story in this historic one-off Test will be the performance of Reece Hodge at No.10. Is he a genuine fly-half back-up?
England will complete a four-year wait to face New Zealand when they clash with the world champions at Twickenham next year.
Ireland head coach Joe Schmidt was relieved to see his side clinch a hard-fought 35-13 victory over Japan at Ajinomoto Stadium in Tokyo.
Simon Zebo and Paddy Jackson return to the starting fold for Ireland as coach Joe Schmidt rotates his side that thrashed USA for Saturday's Test against Japan.
Garry Ringrose is refusing to get distracted by a possible British & Irish Lions call-up as he concentrates on delivering for Ireland during their summer tour of the United States and Japan.
New Zealand Rugby has confirmed the All Blacks will return to Japan next year to face the Brave Blossoms on Nov. 3 at a yet to be confirmed venue.
As with any Rugby World Cup there's always massive issues and talking points that take the limelight -- but what will be on everyone's minds come 2019 in Japan?
|5||United States of America||4||-106||0|
- JPN11thTRIES SCORED 1st New Zealand : 25 Tries ScoredNZL1st925
- JPN10thPOINTS DIFFERENCE 1st New Zealand : 125 Points DifferenceNZL1st-2125