Browns (2-1) at Cowboys (1-2)
1 p.m. ET | Fox
Matchup rating: 54 | Spread: DAL -4.5 (55.5)
What to watch for: Can the Cowboys play with a lead? In three games, they have held the lead for 13 minutes, 27 seconds. The Cowboys are playing a faster pace than any other team, running a play every 19.8 seconds, according to Football Outsiders. Some of that is due to playing catch-up in multi-score deficits. Some of that is by design. But for the Cowboys to flow better, they need their offense to control tempo of the game and protect their defense. To do that, they need to capitalize early and establish a lead. -- Todd Archer
Bold prediction: With his former college QB in the house, Baker Mayfield, Dallas rookie wide receiver CeeDee Lamb breaks out with two TD grabs. He hasn't yet found the end zone, despite racking up 230 yards on 16 catches over three games. -- Jake Trotter
Stat to know: For Cleveland, running back Nick Chubb can become the first Browns player with 100 rushing yards and two rushing touchdowns in three straight games since Jim Brown did it in 1962-63. For Dallas, quarterback Dak Prescott can become the second NFL QB with three straight 400-plus-yard passing games after posting 450 or more in back-to-back games (Ryan Fitzpatrick is the other, doing so in September 2018).
What to know for fantasy: Cowboys wide receiver Amari Cooper is the only player in the NFL with six catches and 80-plus receiving yards in all three weeks this season. See Week 4 rankings.
Betting nugget: The Cowboys are off to their first 0-3 ATS start to a season since 1989 (finished 1-15 straight up and 6-10 ATS that season). Read more.
Trotter's pick: Cowboys 40, Browns 31
Archer's pick: Cowboys 33, Browns 26
FPI prediction: DAL, 66.9% (by an average of 6.1 points)
Matchup must-reads: Despite obstacles, Browns' offense finding its stride in 2-1 start ... What's wrong with Cowboys' defense? 'It's more than one thing' ... Mayfield, Browns' passing attack looking for more ... Cowboys have to 'figure out a way and clean it up' in a hurry