Saints (1-0) at Raiders (1-0)
Monday, 8:15 p.m. ET | ESPN
Matchup rating: 67.5 | Spread: NO -6 (50)
What to watch for: Las Vegas is breaking in a new stadium in the most bittersweet of circumstances. With no fans, there is not much of a homefield advantage to help cover up the Raiders' injury woes at right tackle, where Trent Brown left the opener with a right calf issue and his replacement, Sam Young, suffered a groin injury. Keep an eye, then, on the Raiders' willingness to run the ball if they fall behind early. -- Paul Gutierrez
Bold prediction: Raiders running back Josh Jacobs will end the Saints' remarkable streak of 44 straight games, including the playoffs, without allowing a 100-yard rusher. But Saints running back Alvin Kamara will have more than 100 receiving yards to help make up for the absence of Michael Thomas. -- Mike Triplett
Stat to know: Las Vegas quarterback Derek Carr is completing 71% of his passes since the start of last season, second-best in the NFL to ... Saints QB Drew Brees (73%). Carr has thrown at least one passing touchdown with zero interceptions in five straight games, the second-longest active steak in the NFL and tied for the longest streak of his career.
What to know for fantasy: Saints wide receiver Emmanuel Sanders led the league with four red-zone targets in Week 1 and figures to stay busy with Thomas' role now up for grabs -- if he is healthy enough to play himself. See Week 2 rankings.
Betting nugget: Brees is 9-2 ATS against the Raiders in his career. Read more.
Triplett's pick: Saints 27, Raiders 23
Gutierrez's pick: Saints 31, Raiders 23
FPI prediction: NO, 58.0% (by an average of 2.9 points)
Matchup must-reads: Sources: Saints expect WR Thomas to miss MNF ... Raiders ecstatic to finally open luxurious 'Death Star' Allegiant Stadium ... Saints lock up LB Davis with 3-year extension, source says ... After struggling, Raiders' defense shows up when it matters most