Ravens (6-2) at Patriots (3-5)
8:20 p.m. ET | NBC
Matchup rating: 74.7 | Spread: BAL -7.5 (43)
What to watch for: Can the Patriots play their second straight turnover-free game? That is their best chance to spring the upset. The Patriots have a minus-1 turnover differential on the season (tied for 18th), while the Ravens are plus-4 (tied for sixth). -- Mike Reiss
Bold prediction: The Ravens will score over 40 points for the first time this season. During Baltimore's 10-game road win streak, quarterback Lamar Jackson and the Baltimore offense have averaged more points (32.3) than anyone else away from home. New England, which gave up 37 points last season to the Ravens, has a banged-up defense working on a short week. -- Jamison Hensley
Stat to know: The Patriots have failed to throw a passing touchdown in four straight games. A fifth straight game would match the second-longest streak in franchise history (1983 and 1988); the franchise record of six games was set in 1972. One target to watch for the Pats' efforts to break the streak is wide receiver Jakobi Meyers, who had career highs in receiving yards (169), receptions (12), targets (14) and receiving first downs (8) in the Patriots' win over the Jets on Monday.
What to know for fantasy: Jackson has scored 40.7% of his fantasy points this season with his legs, a rate that isn't much different from last season (40%). The deep ball has been the fantasy-scoring problem, as his points per deep attempt is down 36.3% this season. See Week 10 rankings.
Betting nugget: The Patriots have been a home underdog just three times in the last 15 seasons, winning each game outright. Read more.
Hensley's pick: Ravens 41, Patriots 24
Reiss' pick: Patriots 20, Ravens 17
FPI prediction: BAL, 66.3% (by an average of 5.7 points)
Matchup must-reads: Harbaugh mum on Bryant's role ... Patriots' Newton says neck sore from big Jets hit ... Ravens show resilience after tough week ... Patriots coach Belichick calls Jets exit 'one of the great moments of my career'