Philadelphia's inactives include tackle Lane Johnson, receiver Nelson Agholor, quarterback Nate Sudfeld, defensive end Shareef Miller, offensive lineman Sua Opeta, running back Elijah Holyfield and defensive end Genard Avery. With Johnson and guard Brandon Brooks (shoulder) sidelined, Halapoulivaati Vaitai and guard Matt Pryor will make up the right side of the line. It will be Pryor's first NFL start.
Tight end Zach Ertz (broken rib, lacerated kidney) is active.
The Seahawks' inactives are left guard Mike Iupati, left tackle Duane Brown, wide receivers Jaron Brown and Malik Turner, defensive end L.J. Collier, defensive tackle Bryan Mone and linebacker Mychal Kendricks. Guard Jamarco Jones and George Fant are expected to replace Iupati and Brown on the left side.
With Jaron Brown and Turner out, the Seahawks are down to four available wide receivers today in Tyler Lockett, DK Metcalf, David Moore and John Ursua. Seattle ran the third-most offensive plays this season with at least three wide receivers on the field, so being thin there could be impactful.