To help you set your lineups and avoid starting a player who won't take the field, we will post fantasy-relevant updates and analysis here as NFL teams release their inactives lists, typically about 90 minutes before kickoff. Any rankings cited in this column come from our ESPN Fantasy staff ranks.
Refresh often for the latest information.
4 p.m. ET games
Offense
Marquise Brown, WR, BAL: Ankle -- Inactive
Impact: Missed practice all week. Willie Snead IV/Miles Boykin both benefit with his absence.
Mitchell Trubisky, QB, CHI: Shoulder -- Active
Impact: Practiced in full pads all week, so it is not a surprise that he will start this one.
Michael Badgley, K, LAC: Groin -- Inactive
Impact: Grab whichever waiver-wire kicker you can if you've been left holding the bag here.
Drew Brees, QB, NO: Thumb -- OUT
Impact: Next week is a real possibility. Teddy Bridgewater is to be avoided, given all the other offensive injuries.
Alvin Kamara, RB, NO: Ankle -- OUT
Impact: It will be Latavius Murray, early and often and all of the time.
Tre'Quan Smith, WR, NO: Ankle -- OUT
Impact: Deonte Harris/Lil'Jordan Humphrey become deep-league dart throws.
Jared Cook, TE, NO: Ankle -- OUT
Impact: Dan Arnold promoted from practice squad.
Will Dissly, TE, SEA: Achilles -- OUT
Impact: Out for the year. Luke Willson will try to pick up the slack.
Delanie Walker, TE, TEN: Ankle -- Active
Impact: Jonnu Smith will probably steal snaps, given how many No. 2 TE have shined in the early games.
Defense
Patrick Onwuasor, LB, BAL: Ankle -- Inactive
Bilal Nichols, DE, CHI: Knee -- Active
Melvin Ingram III, DE, LAC: Hamstring -- Inactive
Brandon Mebane, DT, LAC: Knee -- OUT
Justin Jones, DT, LAC: Shoulder -- OUT
Ziggy Ansah, DE, SEA: Ankle -- Inactive
Bradley McDougald, S, SEA: Back -- Inactive
Jayon Brown, LB, TEN: Groin -- Inactive
Cameron Wake, LB, TEN: Hamstring -- Active
Official Sunday inactives should begin coming in at approximately 11:30 a.m. ET for the early games and at 2:30 p.m. ET for the late games.
1 p.m. ET games
Offense
David Johnson, RB, ARI: Ankle -- Active
Impact: Chase Edmonds may still see an increased workload.
Christian Kirk, WR, ARI: Ankle -- Inactive
Impact: Damiere Byrd gets a slight boost in fantasy value.
A.J. Green, WR, CIN: Ankle -- OUT
Impact: Seemingly still not close to return. Tyler Boyd and Auden Tate remain fantasy-viable.
Geronimo Allison, WR, GB: Concussion -- Active
Impact: Upgraded on Saturday and will play, but still risky.
Davante Adams, WR, GB: Toe -- OUT
Impact: Jake Kumerow/Allen Lazard become flex long shots.
Marquez Valdes-Scantling, WR, GB: Ankle -- Active
Impact: Was a game-time call, so you may want to err on the side of caution here.
Marqise Lee, WR, JAX: Ankle -- OUT
Impact: Chris Conley should handle No. 3 WR duties.
Dede Westbrook, WR, JAX: Shoulder -- Active
Impact: Keelan Cole might still get a few extra looks.
Geoff Swaim, TE, JAX: Concussion -- OUT
Impact: Josh Oliver primed to make his NFL debut.
Malcolm Brown, RB, LAR: Ankle -- Inactive
Impact: Todd Gurley II will be back in the huddle in the nick of time.
Jakeem Grant, WR, MIA: Hamstring -- Active
Impact: Albert Wilson, who is also dinged up, is the best of the sad Miami WR bunch.
Sterling Shepard, WR, NYG: Concussion -- OUT
Impact: Limited practices, but won't clear protocol. Go with Golden Tate/Darius Slayton instead.
Tyrell Williams, WR, OAK: Foot -- OUT
Impact: Trevor Davis, Hunter Renfrow are among potential replacements ...
Dwayne Harris, WR, OAK: Ankle -- Inactive
Impact: Zay Jones is also a surprise inactive. Could Keelan Doss shine?
Deebo Samuel, WR, SF: Groin -- OUT
Impact: Not traveling with team. Dante Pettis/Marquise Goodwin get minor value bumps.
Raheem Mostert, RB, SF: Knee -- Active
Impact: With Tevin Coleman back from injury, Mostert's fantasy value is all but zero.
Chris Thompson, RB, WAS: Toe -- OUT
Impact: Wendell Smallwood should be quite active in the passing game.
Vernon Davis, TE, WAS: Concussion -- OUT
Impact: Jeremy Sprinkle hasn't done much with his window of opportunity.
Defense
Zach Allen, DE, ARI: Neck -- OUT
Desmond Trufant, CB, ATL: Toe -- OUT
Matt Milano, LB, BUF: Hamstring -- Inactive
Taron Johnson, CB, BUF: Hamstring -- Active
Carlos Dunlap, DE, CIN: Knee -- Inactive
Darius Slay, CB, DET: Hamstring -- Active
Quandre Diggs, S, DET: Hamstring -- Active
Kenny Clark, DT, GB: Calf -- Active
Darnell Savage, S, GB: Ankle -- OUT
Johnathan Joseph, CB, HOU: Hamstring -- Active
Tashaun Gipson Sr., S, HOU: Hip -- Active
Bradley Roby, CB, HOU: Hamstring -- Inactive
Justin Houston, DE, IND: Calf -- Active
Malik Hooker, S, IND: Knee -- Inactive
Kenny Moore II, CB, IND: Knee -- OUT
Pierre Desir, CB, IND: Abdomen -- Active
Reshad Jones, S, MIA: Chest -- OUT
Xavien Howard, CB, MIA: Knee -- Inactive
Ben Gedeon, LB, MIN: Concussion -- OUT
Arden Key, DE, OAK: Kneecap -- OUT
D.J. Jones, DT, SF: Hamstring -- OUT
Ahkello Witherspoon, CB, SF: Foot -- OUT
Josh Norman, CB, WAS: Thigh -- Inactive