Blackpool manager Gary Bowyer has stepped down after one game of the new season, the League One side said on Monday.
Blackpool began their campaign with a 0-0 draw at Wycombe Wanderers on Saturday, but Bowyer will not be in charge of this weekend's match in a league fixture at home against Portsmouth.
His assistant Terry McPhillips will take charge of the club on an interim basis.
Bowyer, 47, took charge of Blackpool in 2016 after the club were relegated to League Two and secured immediate promotion back to League One in his first season in charge.
"It has been a pleasure to manage Blackpool Football Club over the past two years," he said after becoming the first manager in England's top four divisions to depart this season.
The club did not specify why Bowyer had resigned in a club statement but suggested time with family was a factor.
"We hope the time with your family will bring you much pleasure and rest and replenish your reserves and strengths in readiness for whatever challenge you wish to take on in the future," the statement said.