Ireland coach Andy Farrell has named an unchanged starting 15 from the win against Wales to travel to Twickenham to play England on Sunday.
Leinster's Robbie Henshaw is named in the Irish midfield alongside Connacht's Bundee Aki after coming off early in the previous game for a HIA assessment.
Despite competition from Ulster's John Cooney, Conor Murray stays at scrum-half and lines up alongside captain Johnny Sexton.
- ESPN Fantasy Rugby is back! Click here to pick your team!
Full-back is an all-island affair with Leinster's Jordan Larmour, Munster's Andrew Conway and Ulster's Jacob Stockdale retaining their places.
For the third test match in a row Farrell has opted for Leinster's Cian Healy and Tadhg Furlong alongside Ulster's Rob Herring in the front-row.
Second row is covered by Ulster's Iain Henderson and Leinster's James Ryan while the back-row is made up of Munster's CJ Stander and Peter O'Mahony and Leinster's Josh van der Flier.
Caelan Doris, who had an unfortunate first cap against Scotland when he was knocked unconscious after four minutes, returns to the bench after completing return to play protocols.
Ireland starting XV to face England:
Jordan Larmour, Andrew Conway, Robbie Henshaw, Bundee Aki, Jacob Stockdale, Jonathan Sexton (captain), Conor Murray; Cian Healy, Rob Herring, Tadhg Furlong, Iain Henderson, James Ryan, Peter O'Mahony, Josh van der Flier, CJ Stander
Replacements: Ronan Kelleher, Dave Kilcoyne, Andrew Porter, Devin Toner, Caelan Doris, John Cooney, Ross Byrne, Keith Earls