| 20 May, 2022 | Yorgan De Castro | L | TKO (Injury) | 3 | 0:35 | Eagle FC 47: Eagle Fighting Championship |
| 13 Dec, 2020 | Ciryl Gane | L | KO/TKO | 2 | 2:34 | UFC 256: Figueiredo vs. Moreno |
| 15 Aug, 2020 | Jairzinho Rozenstruik | L | KO/TKO | 2 | 3:47 | UFC 252: Miocic vs. Cormier 3 |
| 25 Jan, 2020 | Curtis Blaydes | L | KO/TKO | 2 | 1:06 | UFC Fight Night: Blaydes vs. Dos Santos |
| 29 Jun, 2019 | Francis Ngannou | L | KO/TKO | 1 | 1:11 | UFC Fight Night: Ngannou vs. Dos Santos |
| 9 Mar, 2019 | Derrick Lewis | W | KO/TKO | 2 | 1:58 | UFC Fight Night: Lewis vs. Dos Santos |
| 1 Dec, 2018 | Tai Tuivasa | W | KO/TKO | 2 | 2:30 | UFC Fight Night: Dos Santos vs. Tuivasa |
| 15 Jul, 2018 | Blagoy Ivanov | W | Decision - Unanimous | 5 | 5:00 | UFC Fight Night: Dos Santos vs. Ivanov |
| 13 May, 2017 | Stipe Miocic | L | KO/TKO | 1 | 2:22 | UFC 211: Miocic vs. dos Santos 2 |
| 10 Apr, 2016 | Ben Rothwell | W | Decision - Unanimous | 5 | 5:00 | UFC Fight Night: Rothwell vs. dos Santos |
| 19 Dec, 2015 | Alistair Overeem | L | KO/TKO | 2 | 4:43 | UFC on Fox: Dos Anjos vs. Cerrone 2 |
| 13 Dec, 2014 | Stipe Miocic | W | Decision - Unanimous | 5 | 5:00 | UFC Fight Night: Dos Santos vs. Miocic |
| 20 Oct, 2013 | Cain Velasquez | L | KO/TKO | 5 | 3:09 | UFC 166: Velasquez vs. Dos Santos 3 |
| 26 May, 2013 | Mark Hunt | W | KO/TKO | 3 | 4:18 | UFC 160: Velasquez vs. Silva 2 |
| 30 Dec, 2012 | Cain Velasquez | L | Decision - Unanimous | 5 | 5:00 | UFC 155: Dos Santos vs. Velasquez 2 |
| 27 May, 2012 | Frank Mir | W | KO/TKO | 2 | 3:04 | UFC 146: dos Santos vs. Mir |
| 13 Nov, 2011 | Cain Velasquez | W | KO/TKO | 1 | 1:04 | UFC on Fox: Velasquez vs. dos Santos |
| 12 Jun, 2011 | Shane Carwin | W | Decision - Unanimous | 3 | 5:00 | UFC 131: Dos Santos vs. Carwin |
| 8 Aug, 2010 | Roy Nelson | W | Decision - Unanimous | 3 | 5:00 | UFC 117: Silva vs. Sonnen |
| 22 Mar, 2010 | Gabriel Gonzaga | W | KO/TKO | 1 | 3:53 | UFC on Versus: Vera vs. Jones |
| 3 Jan, 2010 | Gilbert Yvel | W | KO/TKO | 1 | 2:07 | UFC 108: Evans vs. Silva |
| 20 Sep, 2009 | Mirko Filipovic | W | KO/TKO | 3 | 2:00 | UFC 103: Franklin vs. Belfort |
| 22 Feb, 2009 | Stefan Struve | W | KO/TKO | 1 | 0:54 | UFC 95: Sanchez vs. Stevenson |
| 26 Oct, 2008 | Fabricio Werdum | W | KO/TKO | 1 | 1:21 | UFC 90: Silva vs. Cote |
| 24 May, 2008 | Geronimo dos Santos | W | TKO (Doctor Stoppage) | 1 | - | DF 3: Demo Fight 3 |
| 10 Nov, 2007 | Joaquim Ferreira | L | Submission (Armbar) | 1 | 1:13 | MTL: Final |
| 29 Sep, 2007 | Jair Goncalves | W | TKO | 1 | 2:52 | MTL: Mo Team League 2 |
| 29 Apr, 2007 | Joaquim Ferreira | W | TKO (Retirement) | 1 | 5:00 | XFC: Brazil |
| 29 Apr, 2007 | Edson Ramos | W | TKO (Doctor Stoppage) | 1 | 8:46 | XFC: Brazil |
| 9 Dec, 2006 | Eduardo Maiorino | W | Submission (Guillotine) | 1 | 0:50 | MF 5: Minotauro Fights 5 |
| 16 Jul, 2006 | Jailson Silva Santos | W | KO | 1 | 2:58 | DF 1: Demo Fight 1 |
