| Passing Leaders | |||||||||
| RK | NAME | TEAM | RESULT | COMP | ATT | YDS | TD | INT | RAT |
| 1 | Michael Penix Jr., QB | WASH | W 41-7 at MSU | 27 | 35 | 473 | 4 | 0 | 228.4 |
| 2 | Darren Grainger, QB | GAST | W 41-25 at CLT | 27 | 33 | 466 | 3 | 0 | 230.4 |
| 3 | Dillon Gabriel, QB | OU | W 66-17 at TLSA | 28 | 31 | 421 | 5 | 1 | 251.2 |
| 4 | Drake Maye, QB | UNC | W 31-13 vs. MINN | 29 | 40 | 414 | 2 | 2 | 165.9 |
| 5 | Davis Brin, QB | GASO | L 14-35 at WIS | 33 | 52 | 383 | 1 | 5 | 112.4 |
| 6 | Brayden Fowler-Nicolosi, QB | CSU | L 35-43 at COLO | 34 | 47 | 367 | 3 | 3 | 146.2 |
| 7 | Jayden Daniels, QB | LSU | W 41-14 at MSST | 30 | 34 | 361 | 2 | 0 | 196.8 |
| 8 | Brady Cook, QB | MIZ | W 30-27 vs. KSU | 23 | 35 | 356 | 2 | 0 | 170.0 |
| 9 | Shedeur Sanders, QB | COLO | W 43-35 vs. CSU | 38 | 47 | 348 | 4 | 1 | 166.9 |
| 10 | Kaidon Salter, QB | LIB | W 55-27 at BUFF | 16 | 26 | 344 | 5 | 0 | 236.1 |
| Rushing Leaders | |||||||||
| RK | NAME | TEAM | RESULT | CAR | YDS | YPC | TD | ||
| 1 | Garrett Shrader, QB | SYR | W 35-20 at PUR | 25 | 195 | 7.8 | 4 | ||
| 2 | Nate Noel, RB | APP | W 43-28 vs. ECU | 25 | 193 | 7.7 | 1 | ||
| 3 | Marquez Cooper, RB | BALL | W 45-7 vs. INST | 22 | 177 | 8.0 | 1 | ||
| 4 | Audric Estime, RB | ND | W 41-17 vs. CMU | 20 | 176 | 8.8 | 1 | ||
| 5 | Trevor Etienne, RB | FLA | W 29-16 vs. TENN | 23 | 172 | 7.5 | 1 | ||
| 6 | Blake Watson, RB | MEM | W 28-24 vs. NAVY | 10 | 169 | 16.9 | 1 | ||
| 7 | Jonathon Brooks, RB | TEX | W 31-10 vs. WYO | 21 | 164 | 7.8 | 0 | ||
| Ja'Quez Cross, RB | ARST | W 31-7 vs. STBK | 15 | 164 | 10.9 | 2 | |||
| 9 | Alex Tecza, FB | NAVY | L 24-28 at MEM | 15 | 163 | 10.9 | 1 | ||
| 10 | Tahj Brooks, RB | TTU | W 41-3 vs. TAR | 19 | 158 | 8.3 | 0 | ||
| Receiving Leaders | |||||||||
| RK | NAME | TEAM | RESULT | REC | YDS | YPR | TD | ||
| 1 | Malik Nabers, WR | LSU | W 41-14 at MSST | 13 | 239 | 18.4 | 2 | ||
| 2 | Robert Lewis, WR | GAST | W 41-25 at CLT | 6 | 220 | 36.7 | 2 | ||
| 3 | Rome Odunze, WR | WASH | W 41-7 at MSU | 8 | 180 | 22.5 | 0 | ||
| 4 | Javon Harvey, WR | ODU | L 24-27 vs. WAKE | 3 | 166 | 55.3 | 1 | ||
| 5 | Ricky White, WR | UNLV | W 40-37 vs. VAN | 12 | 165 | 13.8 | 0 | ||
| Nate McCollum, WR | UNC | W 31-13 vs. MINN | 15 | 165 | 11.0 | 1 | |||
| 7 | Jamari Thrash, WR | LOU | W 21-14 at IU | 4 | 159 | 39.8 | 1 | ||
| 8 | Kobe Hudson, WR | UCF | W 48-14 vs. VILL | 6 | 147 | 24.5 | 0 | ||
| 9 | Eric McAlister, WR | BOIS | W 42-18 vs. UND | 6 | 143 | 23.8 | 2 | ||
| 10 | Malik Washington, WR | UVA | L 14-42 at MD | 9 | 141 | 15.7 | 0 | ||