| Passing Leaders | |||||||||
| RK | NAME | TEAM | RESULT | COMP | ATT | YDS | TD | INT | RAT |
| 1 | E.J. Warner, QB | TEM | L 34-49 vs. UTSA | 42 | 65 | 472 | 5 | 0 | 151.0 |
| 2 | Drake Maye, QB | UNC | W 40-7 vs. SYR | 33 | 47 | 442 | 3 | 0 | 170.3 |
| 3 | Brady Cook, QB | MIZ | L 39-49 vs. LSU | 30 | 47 | 411 | 2 | 2 | 142.8 |
| 4 | Nicholas Vattiato, QB | MTSU | L 30-45 vs. JVST | 26 | 41 | 408 | 2 | 2 | 153.3 |
| 5 | Carson Beck, QB | UGA | W 51-13 vs. UK | 28 | 35 | 389 | 4 | 1 | 205.4 |
| 6 | Cooper Legas, QB | USU | W 44-24 vs. CSU | 19 | 29 | 387 | 4 | 2 | 209.3 |
| 7 | JT Daniels, QB | RICE | L 31-38 vs. CONN | 33 | 49 | 362 | 2 | 1 | 138.8 |
| 8 | Jacob Zeno, QB | UAB | W 56-35 vs. USF | 19 | 25 | 353 | 4 | 1 | 239.4 |
| 9 | Quinn Ewers, QB | TEX | L 30-34 vs. OU | 31 | 37 | 346 | 1 | 2 | 160.4 |
| 10 | Frank Harris, QB | UTSA | W 49-34 at TEM | 25 | 33 | 338 | 3 | 0 | 191.8 |
| Rushing Leaders | |||||||||
| RK | NAME | TEAM | RESULT | CAR | YDS | YPC | TD | ||
| 1 | Antario Brown, RB | NIU | W 55-14 at AKR | 13 | 280 | 21.5 | 4 | ||
| 2 | Kimani Vidal, RB | TROY | W 37-3 vs. ARST | 28 | 245 | 8.8 | 3 | ||
| 3 | Trey Benson, RB | FSU | W 39-17 vs. VT | 11 | 200 | 18.2 | 2 | ||
| 4 | Ismail Mahdi, RB | TXST | L 30-34 at UL | 34 | 188 | 5.5 | 1 | ||
| 5 | Dequan Finn, QB | TOL | W 41-24 at MASS | 13 | 172 | 13.2 | 1 | ||
| 6 | Tahj Brooks, RB | TTU | W 39-14 at BAY | 31 | 170 | 5.5 | 1 | ||
| 7 | Ashton Jeanty, RB | BOIS | W 35-27 vs. SJSU | 24 | 167 | 7.0 | 0 | ||
| 8 | Kay'Ron Lynch-Adams, RB | MASS | L 24-41 vs. TOL | 20 | 157 | 7.9 | 1 | ||
| 9 | Devin Neal, RB | KU | W 51-22 vs. UCF | 12 | 154 | 12.8 | 1 | ||
| 10 | Emani Bailey, RB | TCU | L 14-27 at ISU | 21 | 152 | 7.2 | 0 | ||
| Receiving Leaders | |||||||||
| RK | NAME | TEAM | RESULT | REC | YDS | YPR | TD | ||
| 1 | Malachi Corley, WR | WKU | W 35-28 at LT | 8 | 207 | 25.9 | 3 | ||
| 2 | Jermaine Burton, WR | ALA | W 26-20 at TA&M | 9 | 197 | 21.9 | 2 | ||
| 3 | Eric McAlister, WR | BOIS | W 35-27 vs. SJSU | 5 | 170 | 34.0 | 1 | ||
| 4 | Marvin Harrison Jr., WR | OSU | W 37-17 vs. MD | 8 | 163 | 20.4 | 1 | ||
| 5 | CJ Daniels, WR | LIB | W 21-16 vs. SHSU | 5 | 157 | 31.4 | 1 | ||
| 6 | Caullin Lacy, WR | USA | W 55-7 at ULM | 7 | 156 | 22.3 | 1 | ||
| 7 | Luther Burden III, WR | MIZ | L 39-49 vs. LSU | 11 | 149 | 13.5 | 0 | ||
| 8 | Malik Nabers, WR | LSU | W 49-39 at MIZ | 6 | 146 | 24.3 | 1 | ||
| 9 | Terrell Vaughn, WR | USU | W 44-24 vs. CSU | 8 | 143 | 17.9 | 1 | ||
| 10 | Anthony Simpson, WR | MASS | L 24-41 vs. TOL | 7 | 140 | 20.0 | 1 | ||