| Passing Leaders | |||||||||||
| PLAYER | TEAM | RESULT | COMP | ATT | YDS | TD | INT | SACK | FUM | RAT | |
Dak Prescott |
1. Dak Prescott, QB | DAL | L 48-32 vs. GB | 41 | 60 | 403 | 3 | 2 | 4 | 0 | 89.8 |
| 2. Matthew Stafford, QB | LAR | L 24-23 at DET | 25 | 36 | 367 | 2 | 0 | 2 | 0 | 120.9 | |
| 3. Baker Mayfield, QB | TB | W 32-9 vs. PHI | 22 | 36 | 337 | 3 | 0 | 4 | 0 | 119.8 | |
| 4. Joe Flacco, QB | CLE | L 45-14 at HOU | 34 | 46 | 307 | 1 | 2 | 4 | 0 | 80.6 | |
| 5. Jared Goff, QB | DET | W 24-23 vs. LAR | 22 | 27 | 277 | 1 | 0 | 3 | 0 | 121.8 | |
| Rushing Leaders | ||||||||||
| PLAYER | TEAM | RESULT | CAR | YDS | AVG | TD | LNG | FUM | ||
Aaron Jones |
1. Aaron Jones, RB | GB | W 48-32 at DAL | 21 | 118 | 5.6 | 3 | 27 | 0 | |
| 2. Isiah Pacheco, RB | KC | W 26-7 vs. MIA | 24 | 89 | 3.7 | 1 | 23 | 0 | ||
| 3. James Cook, RB | BUF | W 31-17 vs. PIT | 18 | 79 | 4.4 | 0 | 12 | 0 | ||
| 4. Josh Allen, QB | BUF | W 31-17 vs. PIT | 8 | 74 | 9.3 | 1 | 52 | 0 | ||
| 5. Rachaad White, RB | TB | W 32-9 vs. PHI | 18 | 72 | 4.0 | 0 | 12 | 0 | ||
| Receiving Leaders | ||||||||||
| PLAYER | TEAM | RESULT | REC | YDS | AVG | TD | LNG | FUM | ||
Puka Nacua |
1. Puka Nacua, WR | LAR | L 24-23 at DET | 9 | 181 | 20.1 | 1 | 50 | 0 | |
| 2. Romeo Doubs, WR | GB | W 48-32 at DAL | 6 | 151 | 25.2 | 1 | 46 | 0 | ||
| 3. DeVonta Smith, WR | PHI | L 32-9 at TB | 8 | 148 | 18.5 | 0 | 55 | 0 | ||
| 4. Rashee Rice, WR | KC | W 26-7 vs. MIA | 8 | 130 | 16.3 | 1 | 39 | 0 | ||
| 5. CeeDee Lamb, WR | DAL | L 48-32 vs. GB | 9 | 110 | 12.2 | 0 | 47 | 0 | ||
| Defensive Leaders | ||||||||||
| PLAYER | TEAM | RESULT | SOLO | AST | TOT | SACK | FF | INT | TD | |
Desmond King II |
1. Desmond King II, CB | HOU | W 45-14 vs. CLE | 7 | 5 | 12 | 0.0 | 0 | 0 | 0 |
| 2. A.J. Klein, LB | BUF | W 31-17 vs. PIT | 7 | 4 | 11 | 0.0 | 0 | 0 | 0 | |
| 3. Keisean Nixon, CB | GB | W 48-32 at DAL | 7 | 4 | 11 | 1.0 | 0 | 0 | 0 | |
| 4. Quay Walker, LB | GB | W 48-32 at DAL | 4 | 7 | 11 | 0.0 | 0 | 0 | 0 | |
| 5. Jamel Dean, CB | TB | W 32-9 vs. PHI | 9 | 1 | 10 | 0.0 | 0 | 0 | 0 | |