<
>
EXCLUSIVE CONTENT
Get ESPN+

The Playbook, Week 2: Bills, 49ers most likely to win

Josh Allen and the Buffalo Bills will host the Las Vegas Raiders for their home opener on Sunday in what should be a more appealing matchup than in their Week 1 loss to the New York Jets. Michael Owens/Getty Images

Welcome to the Week 2 Fantasy Football Playbook, which kicks off Thursday night with the Vikings at Eagles.

This column features score projections, over/unders, win probabilities and, of course, easily digestible fantasy advice for season-long and DFS leagues. This guide should help you with all sorts of decision-making, including sit/start decisions, last-minute waiver adds and lineup choices.

The advice is centered on 12-team PPR leagues with relatively standard scoring and lineup settings (1 QB, 2 RB, 3 WR, 1 Flex, 1 K, 1 D/ST), although I'll often mention "shallow" or "deep" leagues for some starters. The charts show all players who have been projected for at least 6.0 fantasy points this week, as well as all D/STs. "Matchup" is automatically determined using a proprietary metric that factors in raw and volume-adjusted fantasy points allowed to each position by the opposing defense this season.

(Editor's note: Projections and rankings will align almost perfectly, but sometimes when a projection is close, a player might be ranked slightly higher or lower because of other factors, including upside or risk. This column is subject to possible updates during the weekend, although at the very minimum, rankings will be updated on the site and projections will always be updated inside the game leading up to kickoff. Lines courtesy of Caesars Sportsbook unless otherwise indicated.)