- César Haydar (4')
- Walmer Pacheco (25')
- Carlos Bacca (51')
- Fernando Uribe (69')
- Jaen Pineda (58')
- Jorge Segura (90'+4')
Metropolitano Roberto Meléndez
1:45 AM, 14 August 2022
- Wander Mosquera Mena
Match ends, Junior 4, Independiente Medellín 2.
Second Half ends, Junior 4, Independiente Medellín 2.
Goal! Junior 4, Independiente Medellín 2. Jorge Segura (Independiente Medellín) header from very close range to the centre of the goal. Assisted by Adrián Arregui with a headed pass following a set piece situation.
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