Marcus Bingham made a pair of foul shots for Michigan State with 78 seconds left to cap the scoring.
Michigan State guard Josh Langford missed the front end of a 1-and-1 with eight seconds left. But the Nittany Lions couldn't take advantage as Myles Dread's contested 3-pointer from the left side wasn't close as time expired.
Penn State led 58-54 with 3:16 remaining after Myreon Jones made a pair of foul shots, but they went scoreless the rest of the way. Jones' layup at 4:59 marked Penn State's last field goal as the Nittany Lions missed their next six shots. Jones scored Penn State's final eight points.
The Spartans (10-7, 4-7 Big Ten Conference) extended their 32-24 halftime lead to 12 points early in the second stanza before the Nittany Lions gradually began their return. Jones' layup with 6:16 left gave Penn State a 52-51 lead, its first since 4-3.
John Harrar tied career highs with 17 points and 14 rebounds for Penn State (7-9, 4-8). It was the second time he reached the 17-point mark and third time corralling 14 boards. Jones finished with 15 points.
The Spartans, who moved their all-time record to 41-9 against Penn State, host No. 15 Iowa on Saturday. Penn State hosts Nebraska on Sunday.
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