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San Francisco
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12-5
2nd in NFC West
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4 Jan
Dee Winters
LB
Status
Questionable
Winters could miss the wild-card round of the NFC playoffs due to an ankle injury he sustained during the 49ers' 13-3 loss to the Seahawks on Saturday, Noah Furtado and Eric Branch of the San Francisco Chronicle report.
Tatum Bethune
LB
Status
Questionable
Head coach Kyle Shanahan told reporters after the 49ers' 13-3 loss to the Seahawks on Saturday that Bethune's groin injury could prevent him from playing in the wild-card round of the NFC playoffs, Noah Furtado and Eric Branch of the San Francisco Chronicle report.
Brock Purdy
QB
Status
Questionable
San Francisco head coach Kyle Shanahan relayed that Purdy suffered a "stinger" after taking a hard hit to his left shoulder on the 49ers' final offensive play of Saturday's 13-3 loss to the Seahawks, Noah Furtado and Eric Branch of the San Francisco Chronicle report. "It's just I got hit, and the left shoulder sort of lit up," Purdy said after the contest. "I feel good right now. We'll see how I feel [Sunday]."
Trent Williams
OT
Status
Out
Williams (hamstring) is inactive for Saturday night's game against the Seahawks, Briana Jeannel of the 49ers' official site reports.
3 Jan
Curtis Robinson
LB
Status
Out
Robinson (coach's decision) is inactive for Saturday night's game against the Seahawks, Briana Jeannel of the 49ers' official site reports.
Ricky Pearsall
WR
Status
Out
Pearsall (knee/ankle) is inactive for Saturday's game against the Seahawks, Briana Jeannel of the 49ers' official site reports.
Chase Lucas
CB
Status
Out
Isaac Guerendo
RB
Status
Out
Kevin Givens
DT
Status
Out
Robert Beal Jr.
DE
Status
Out
31 Dec
Jacob Cowing
WR
Status
Injured reserve
San Francisco head coach Kyle Shanahan said Friday that Cowing (hamstring) could have his 21-day practice window opened during Week 18 prep, Matt Barrows of The Athletic reports.
29 Dec
Kurtis Rourke
QB
Status
Out
Rourke (knee) will remain on the 49ers' reserve/non-football injury list for the rest of the 2025 season, Matt Maiocco of NBC Sports Bay Area reports.
27 Dec
Fred Warner
LB
Status
Injured reserve
Warner (ankle) is ahead of schedule in his recovery and could be a candidate to return to action if the 49ers make a deep playoff run, Ian Rapoport and Mike Garafolo of NFL Network report.
20 Dec
Nick Martin
LB
Status
Injured reserve
The 49ers placed Martin (concussion) on injured reserve Saturday.
13 Dec
Brandon Aiyuk
WR
Status
Out
The 49ers placed Aiyuk (knee) on the reserve/left squad list Saturday, Matt Barrows of The Athletic reports.
9 Dec
Ben Bartch
G
Status
Injured reserve
The 49ers placed Bartch (foot) on injured reserve Monday.
9 Nov
Mykel Williams
DE
Status
Injured reserve
The 49ers placed Williams (knee) on injured reserve Saturday.
26 Sep
Nick Bosa
DE
Status
Injured reserve
Bosa (knee) underwent surgery to address his torn ACL on Friday, Cam Inman of The San Jose Mercury News reports.
28 Aug
Jakob Robinson
CB
Status
Injured reserve
Robinson (forearm) was placed on injured reserve Tuesday.
20 Aug
Patrick Taylor Jr.
RB
Status
Injured reserve
Taylor will undergo season-ending surgery to repair a fracture in his shoulder, Nick Wagoner of ESPN.com reports.
29 Jul
Tarron Jackson
DE
Status
Injured reserve
Jackson (undisclosed) was discharged from the hospital and returned to the 49ers' training camp Monday, Matt Maiocco of NBC Sports Bay Area reports.
4 Jun
Trent Taylor
WR
Status
Injured reserve
The 49ers placed Taylor (undisclosed) on injured reserve Tuesday.
13 May
Tre Tomlinson
CB
Status
Injured reserve
Tomlinson (undisclosed) reverted to the 49ers' injured reserve Tuesday, per the NFL's transaction log.