Gore's 100-yard rushing game was the first for the Golden Eagles' since De'Michael Harris did it on Nov. 16, 2019.
Abram threw a 22-yard touchdown pass to Demarcus Jones and Gore ran it in from 11 yards out to give Southern Mississippi a 14-3 lead in the game's first 4 1/2 minutes.
The Mean Green's Tre Siggers capped an 80-yard scoring drive with a 1-yard scoring run with 1:54 before halftime. But Southern Mississippi (1-3, 1-1 Conference USA) drove 46 yards in 70 seconds, and Briggs Bourgeois kicked a 46-yard field goal to put the Golden Eagles up 20-10 at intermission.
Mayberry's 4-yard scoring run early in the fourth quarter stretched Southern Mississippi to its largest lead at 34-17.
Austin Aune threw for 330 yards and two scores for North Texas (1-2, 0-1).
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Quinn Ewers, the top quarterback in the 2022 class, is skipping his senior year of high school to join Ohio State.
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Top 15 overall prospect Jaheim Singletary decommits from Ohio State Buckeyes
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