| MLB First Round Draft Picks - 1992 | ||||
| PICK | PLAYER | POS | TEAM | SCHOOL/HOMETOWN |
| 1 | Phil Nevin | 3B | Houston Astros | Cal State Fullerton |
| 2 | Paul Shuey | RHP | Cleveland Indians | U of North Carolina |
| 3 | Billy Wallace | LHP | Montreal Expos | Mississippi State U |
| 4 | Jeffrey Hammonds | OF | Baltimore Orioles | Stanford U |
| 5 | Chad Mottola | OF | Cincinnati Reds | Central Florida U |
| 6 | Derek Jeter | SS | New York Yankees | Kalamazzo, MI |
| 7 | Calvin Murray | OF-3B | San Francisco Giants | U of Texas |
| 8 | Pete Janicki | RHP | California Angels | U of California |
| 9 | Preston Wilson | SS-OF | New York Mets | Bamberg, SC |
| 10 | Michael Tucker | SS-2B | Kansas City Royals | Longwood College |
| 11 | Derek Wallace | RHP | Chicago Cubs | Pepperdine U |
| 12 | Kenneth Felder | OF | Milwaukee Brewers | Florida State U |
| 13 | Chad McConnell | OF | Philadelphia Phillies | Creighton U |
| 14 | Ronald Villone | LHP | Seattle Mariners | U of Massachusetts |
| 15 | Jonathan Lowe | RHP | St. Louis Cardinals | Arizona State U |
| 16 | Richard Greene | RHP | Detroit Tigers | Louisiana State U |
| 17 | James Pittsley | RHP | Kansas City Royals | Dubois, PA |
| 18 | Christopher Roberts | OF-LH | New York Mets | Florida State U |
| 19 | Shannon Stewart | OF | Toronto Blue Jays | Miami, FL |
| 20 | Michael Grigsby | RHP | Oakland Athletics | San Diego State U |
| 21 | James Arnold | RHP | Atlanta Braves | Kissimmee, FL |
| 22 | Ricky Helling | RHP | Texas Rangers | Stanford U |
| 23 | Jason Kendall | C | Pittsburgh Pirates | Torrance, CA |
| 24 | Eddie Pearson | 3B | Chicago White Sox | Bishop St JC |
| 25 | Todd Steverson | OF | Toronto Blue Jays | Arizona State U |
| 26 | Daniel Serafini | LHP | Minnesota Twins | San Bruno, CA |
| 27 | John Burke | RHP | U of Florida | |
| 28 | Charles Johnson | C | U of Miami | |