| MLB First Round Draft Picks - Pittsburgh Pirates | ||||
| SEASON | PLAYER | POS | SCHOOL/HOMETOWN | PICK |
| 2016 | Will Craig | 1B | Wake Forest | 22 |
| 2015 | Ke'Bryan Hayes | 3B | Concordia Lutheran HS (Tomball, Texas) | 32 |
| 2015 | Kevin Newman | SS | Arizona | 19 |
| 2014 | Cole Tucker | SS | Mountain Pointe HS, Phoenix | 24 |
| 2013 | Reese McGuire | C | Kentwood High School, Covington, Wash. | 14 |
| 2013 | Austin Meadows | CF | Grayson High School, Loganville, Ga. | 9 |
| 2012 | Mark Appel | RHP | Stanford | 8 |
| 2011 | Gerrit Cole | RHP | UCLA | 1 |
| 2010 | Jameson Taillon | RHP | The Woodlands (Texas) HS | 2 |
| 2009 | Tony Sanchez | C | Boston College | 4 |
| 2008 | Pedro Alvarez | 3B | Vanderbilt | 2 |
| 2007 | Daniel Moskos | LHP | Clemson | 4 |
| 2006 | Brad Lincoln | RHP | Houston | 4 |
| 2005 | Andrew McCutchen | CF | Fort Meade HS (FL) | 11 |
| 2004 | Neil Walker | C | Pine Richland HS, Gibsonia, PA | 11 |
| 2003 | Paul Maholm | LHP | Mississippi State U. | 8 |
| 2002 | Bryan Bullington | RHP | Ball State | 1 |
| 2001 | John VanBenschoten | 1B-OF | Kent State U | 8 |
| 2000 | Sean Burnett | LHP | Wellington, FL | 19 |
| 1999 | Bobby Bradley | RHP | W. Palm Beach, FL | 8 |
| 1998 | Clinton Johnston | LHP | Vanderbilt U. | 15 |
| 1997 | J.J. Davis | 1B | Pomona, CA | 8 |
| 1996 | Kris Benson | RHP | Clemson U | 1 |
| 1995 | Chad Hermansen | SS | Henderson, NV | 10 |
| 1994 | Mark Farris | OF | Angleton, TX | 11 |
| 1993 | Charles Peterson | OF | Laurens, SC | 22 |
| 1992 | Jason Kendall | C | Torrance, CA | 23 |
| 1991 | Jonathan Farrell | OF | Florida CC | 24 |
| 1990 | Kurt Miller | RHP | Bakersfield, CA | 5 |
| 1989 | Willie Greene | SS | Gray, GA | 18 |
| 1988 | Austin Manahan | SS | Phoenix, AZ | 13 |
| 1987 | Mark Merchant | OF | Oviedo, FL | 2 |
| 1986 | Jeff King | 3B | U of Arkansas | 1 |
| 1985 | Barry Bonds | OF | Arizona State U | 6 |
| 1984 | Kevin Andersh | LHP | U of New Mexico | 15 |
| 1983 | Ron DeLucchi | OF | Moraga, CA | 12 |
| 1982 | Sam Khalifa | SS | Tucson, AZ | 7 |
| 1981 | Jim Winn | RHP | John Brown U | 14 |
| 1980 | Rich Renteria | SS | South Gate, CA | 20 |
| 1978 | Gerry Aubin | OF | Albany, GA | 21 |
| 1978 | Brad Garnett | 1B | DeSoto, TX | 19 |
| 1977 | Anthony Nicely | OF | Dayton, OH | 18 |
| 1976 | Jim Parke | RHP | Sterling Heights, MI | 21 |
| 1975 | Dale Berra | SS | Montclair, NJ | 20 |
| 1974 | Rod Scurry | LHP | Sparks, NV | 11 |
| 1973 | Steve Nicosia | C | N. Miami Beach, FL | 24 |
| 1972 | Dwayne Peltier | SS | Anaheim, CA | 23 |
| 1971 | Craig Reynolds | SS | Houston, TX | 22 |
| 1970 | John Bedard | RHP | Springfield, MA | 13 |
| 1969 | Bob May | RHP | Merritt Island, FL | 10 |
| 1968 | Dick Sharon | OF | Redwood City, CA | 9 |
| 1967 | Joe Grigas | OF | Brockton, MA | 16 |
| 1966 | Richie Hebner | SS | Norwood, MA | 15 |
| 1965 | Doug Dickerson | OF | Birmingham, AL | 10 |