| 1981 MLB Leaders | ||
| 1981 American League Standings | |||||||||
| EAST | W | L | PCT | GB | HOME | ROAD | RS | RA | DIFF |
| x-Milwaukee | 62 | 47 | .569 | -- | -- | -- | 493 | 459 | +34 |
| Baltimore | 59 | 46 | .562 | 1 | -- | -- | 429 | 437 | -8 |
| New York | 59 | 48 | .551 | 2 | -- | -- | 421 | 343 | +78 |
| Detroit | 60 | 49 | .550 | 2 | -- | -- | 427 | 404 | +23 |
| Boston | 59 | 49 | .546 | 2.5 | -- | -- | 519 | 481 | +38 |
| Cleveland | 52 | 51 | .505 | 7 | -- | -- | 431 | 442 | -11 |
| Toronto | 37 | 69 | .349 | 23.5 | -- | -- | 329 | 466 | -137 |
| WEST | W | L | PCT | GB | HOME | ROAD | RS | RA | DIFF |
| *-Oakland | 64 | 45 | .587 | -- | -- | -- | 458 | 403 | +55 |
| Texas | 57 | 48 | .543 | 5 | -- | -- | 452 | 389 | +63 |
| Chicago | 54 | 52 | .509 | 8.5 | -- | -- | 476 | 423 | +53 |
| Kansas City | 50 | 53 | .485 | 11 | -- | -- | 397 | 405 | -8 |
| California | 51 | 59 | .464 | 13.5 | -- | -- | 476 | 453 | +23 |
| Seattle | 44 | 65 | .400 | 20 | -- | -- | 426 | 521 | -95 |
| Minnesota | 41 | 68 | .373 | 23 | -- | -- | 378 | 486 | -108 |
| 1981 National League Standings | |||||||||
| EAST | W | L | PCT | GB | HOME | ROAD | RS | RA | DIFF |
| x-St. Louis | 59 | 43 | .573 | -- | -- | -- | 464 | 417 | +47 |
| Montreal | 60 | 48 | .556 | 2 | -- | -- | 443 | 394 | +49 |
| Philadelphia | 59 | 48 | .551 | 2.5 | -- | -- | 491 | 472 | +19 |
| Pittsburgh | 46 | 56 | .447 | 13 | -- | -- | 407 | 425 | -18 |
| New York | 41 | 62 | .390 | 18.5 | -- | -- | 348 | 432 | -84 |
| Chicago | 38 | 65 | .358 | 21.5 | -- | -- | 370 | 483 | -113 |
| WEST | W | L | PCT | GB | HOME | ROAD | RS | RA | DIFF |
| *-Cincinnati | 66 | 42 | .611 | -- | -- | -- | 464 | 440 | +24 |
| Los Angeles | 63 | 47 | .573 | 4 | -- | -- | 450 | 356 | +94 |
| Houston | 61 | 49 | .555 | 6 | -- | -- | 394 | 331 | +63 |
| San Francisco | 56 | 55 | .505 | 11.5 | -- | -- | 427 | 414 | +13 |
| Atlanta | 50 | 56 | .467 | 15 | -- | -- | 395 | 416 | -21 |
| San Diego | 41 | 69 | .373 | 26 | -- | -- | 382 | 455 | -73 |
| 1981 All-Star Results | |||||||||
| DATE | SCORE | VENUE | LOCATION | ATT | WP | LP | MVP | ||
| August 9, 1981 | NL 5, AL 4 | Municipal Stadium | Cleveland, OH | 72,086 | Vida Blue | Rollie Fingers | Gary Carter | ||
| Rosters | Complete Results | |||||||||
| 1981 Postseason Results | ||
| ROUND | OUTCOME | RESULT |
| World Series | Los Angeles Dodgers defeated New York Yankees | 4-2 |
| League Championship Series | New York Yankees defeated Oakland Athletics | 3-0 |
| League Championship Series | Los Angeles Dodgers defeated Montreal Expos | 3-2 |
| Complete Results | ||
| 1981 Award Winners | ||
| PLAYER | TEAM | AWARD |
| No award winners. | ||
| Complete Results | ||
| 1981 Draft Picks | |||
| PLAYER | POS | TEAM | |
| 1 | Mike Moore | RHP | Seattle Mariners |
| 2 | Joe Carter | OF | Chicago Cubs |
| 3 | Dick Schofield | SS | California Angels |
| 4 | Terry Blocker | OF | New York Mets |
| 5 | Matt Williams | RHP | Toronto Blue Jays |
| Complete Results | |||
| 1981 No-Hitters | ||||||
| DATE | PITCHER | TEAM | OPPONENT | SCORE | LEAGUE | NOTES |
| 9/26/1981 | Nolan Ryan | HOU | LA | 5-0 | NL | |
| 5/15/1981 | Len Barker | CLE | TOR | 3-0 | AL | Perfect Game |
| 5/10/1981 | Charlie Lea | MTL | SFO | 4-0 | NL | |
| Complete Results | ||||||