San Francisco 49ers @ Buffalo Bills
Game Leaders

161
S. HillQB
14/23, 1 TD
161

112
T. EdwardsQB
10/21
112

66
F. GoreRB
24 CAR
66

134
M. LynchRB
16 CAR
134

67
I. BruceWR
5 REC, 1 TD
67

80
L. EvansWR
7 REC
80

1
J. SmithDE
1

2
R. DenneyDE
2

14
P. WillisLB
10 SOLO
14

7
C. KelsayDE
5 SOLO
7
Team Stats
195
Total Yards
350
1
Turnovers
1
12
1st Downs
18
4-35
Penalties
6-43
7/15
3rd Down
7/15
0/0
4th Down
0/2
1/2
Red Zone
0/4
29:30
Possession
30:30
Game Information
Orchard Park, NY

Referee:Bill Carollo

Team Stats
| 1st Downs | 12 | 18 |
| Passing 1st downs | 8 | 11 |
| Rushing 1st downs | 2 | 7 |
| 1st downs from penalties | 2 | 0 |
| 3rd down efficiency | 7-15 | 7-15 |
| 4th down efficiency | 0-0 | 0-2 |
| Total Plays | 55 | 66 |
| Total Yards | 195 | 350 |
| Total Drives | 10 | 10 |
| Yards per Play | 3.5 | 5.3 |
| Passing | 133 | 194 |
| Comp/Att | 14/23 | 21/38 |
| Yards per pass | 5.1 | 4.7 |
| Interceptions thrown | 0 | 0 |
| Sacks-Yards Lost | 3-28 | 3-11 |
| Rushing | 62 | 156 |
| Rushing Attempts | 29 | 25 |
| Yards per rush | 2.1 | 6.2 |
| Red Zone (Made-Att) | 1-2 | 0-4 |
| Penalties | 4-35 | 6-43 |
| Turnovers | 1 | 1 |
| Fumbles lost | 1 | 1 |
| Interceptions thrown | 0 | 0 |
| Defensive / Special Teams TDs | 0 | 0 |
| Possession | 29:30 | 30:30 |
2025 Standings
National Football Conference
| NFC West | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| Seattle | 14 | 3 | 0 | .824 | 483 | 292 |
| Los Angeles | 12 | 5 | 0 | .706 | 518 | 346 |
| San Francisco | 12 | 5 | 0 | .706 | 437 | 371 |
| Arizona | 3 | 14 | 0 | .176 | 355 | 488 |
American Football Conference
| AFC East | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| New England | 14 | 3 | 0 | .824 | 490 | 320 |
| Buffalo | 12 | 5 | 0 | .706 | 481 | 365 |
| Miami | 7 | 10 | 0 | .412 | 347 | 424 |
| New York | 3 | 14 | 0 | .176 | 300 | 503 |
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