Buffalo Bills @ San Francisco 49ers
2-3, 1-2 Away
3
2-3, 1-2 Away
4-1, 2-0 Home
45
4-1, 2-0 Home
Game Leaders
126
R. FitzpatrickQB
16/26, 1 INT
126
303
A. SmithQB
18/24, 3 TD
303
35
B. SmithWR
1 CAR
35
106
F. GoreRB
14 CAR, 1 TD
106
40
S. ChandlerTE
4 REC
40
113
M. CrabtreeWR
6 REC, 1 TD
113
--
None
--
1
A. BrooksLB
1
6
G. WilsonSS
6 SOLO
6
7
P. WillisLB
7 SOLO
7
Team Stats
204
Total Yards
621
2
Turnovers
1
10
1st Downs
29
5-30
Penalties
7-53
2/10
3rd Down
7/11
0/0
4th Down
1/1
0/0
Red Zone
0/0
23:46
Possession
36:14
Game Information
San Francisco, CA
Referee:Jerome Boger
Team Stats
 | | |
|---|---|---|
| 1st Downs | 10 | 29 |
| Passing 1st downs | 6 | 11 |
| Rushing 1st downs | 4 | 18 |
| 1st downs from penalties | 0 | 0 |
| 3rd down efficiency | 2-10 | 7-11 |
| 4th down efficiency | 0-0 | 1-1 |
| Total Plays | 46 | 63 |
| Total Yards | 204 | 621 |
| Total Drives | 12 | 10 |
| Yards per Play | 4.4 | 9.9 |
| Passing | 115 | 310 |
| Comp/Att | 16/26 | 19/25 |
| Yards per pass | 4.3 | 12.4 |
| Interceptions thrown | 1 | 0 |
| Sacks-Yards Lost | 1-11 | 0-0 |
| Rushing | 89 | 311 |
| Rushing Attempts | 19 | 38 |
| Yards per rush | 4.7 | 8.2 |
| Red Zone (Made-Att) | 0-0 | 0-0 |
| Penalties | 5-30 | 7-53 |
| Turnovers | 2 | 1 |
| Fumbles lost | 1 | 1 |
| Interceptions thrown | 1 | 0 |
| Defensive / Special Teams TDs | 0 | 0 |
| Possession | 23:46 | 36:14 |
2025 Standings
American Football Conference
| AFC East | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| New England | 14 | 3 | 0 | .824 | 490 | 320 |
| Buffalo | 12 | 5 | 0 | .706 | 481 | 365 |
| Miami | 7 | 10 | 0 | .412 | 347 | 424 |
| New York | 3 | 14 | 0 | .176 | 300 | 503 |
National Football Conference
| NFC West | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| Seattle | 14 | 3 | 0 | .824 | 483 | 292 |
| Los Angeles | 12 | 5 | 0 | .706 | 518 | 346 |
| San Francisco | 12 | 5 | 0 | .706 | 437 | 371 |
| Arizona | 3 | 14 | 0 | .176 | 355 | 488 |
NFL News
How Oreo cookies helped shape the Commanders' rebrand
Before overseeing Washington's uniform overhaul, team president Mark Clouse helped guide one of America's most recognizable brands.
6h
Fantasy football sleepers, busts and breakouts for 2026
Which players will surprise, disappoint or make a big jump this fantasy season? Our analysts give their picks.
6h
How Chiefs' cornerback competition became camp's top battle
The Chiefs enter camp with battle at cornerback, where six players, including Mansoor Delane, are vying for roles.
11h