San Francisco 49ers @ Buffalo Bills
Game Leaders
Team Stats
300
Total Yards
492
1
Turnovers
2
16
1st Downs
29
6-52
Penalties
7-71
3/13
3rd Down
8/13
0/2
4th Down
0/0
0/2
Red Zone
4/4
24:49
Possession
35:11
Game Information
Orchard Park, NY

Line Judge:Gary Arthur
Back Judge:Dino Paganelli
Umpire:Bill Schuster
Referee:Gene Steratore
Field Judge:Mike Weatherford
Side Judge:Bob Waggoner
Down Judge:Ed Walker

Team Stats
| 1st Downs | 16 | 29 |
| Passing 1st downs | 7 | 10 |
| Rushing 1st downs | 8 | 16 |
| 1st downs from penalties | 1 | 3 |
| 3rd down efficiency | 3-13 | 8-13 |
| 4th down efficiency | 0-2 | 0-0 |
| Total Plays | 60 | 74 |
| Total Yards | 300 | 492 |
| Total Drives | 13 | 13 |
| Yards per Play | 5.0 | 6.6 |
| Passing | 167 | 179 |
| Comp/Att | 13/29 | 16/27 |
| Yards per pass | 5.2 | 6.0 |
| Interceptions thrown | 0 | 0 |
| Sacks-Yards Lost | 3-20 | 3-0 |
| Rushing | 133 | 313 |
| Rushing Attempts | 28 | 44 |
| Yards per rush | 4.8 | 7.1 |
| Red Zone (Made-Att) | 0-2 | 4-4 |
| Penalties | 6-52 | 7-71 |
| Turnovers | 1 | 2 |
| Fumbles lost | 1 | 2 |
| Interceptions thrown | 0 | 0 |
| Defensive / Special Teams TDs | 0 | 0 |
| Possession | 24:49 | 35:11 |
2025 Standings
National Football Conference
| NFC West | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| Seattle | 14 | 3 | 0 | .824 | 483 | 292 |
| Los Angeles | 12 | 5 | 0 | .706 | 518 | 346 |
| San Francisco | 12 | 5 | 0 | .706 | 437 | 371 |
| Arizona | 3 | 14 | 0 | .176 | 355 | 488 |
American Football Conference
| AFC East | W | L | T | PCT | PF | PA |
|---|---|---|---|---|---|---|
| New England | 14 | 3 | 0 | .824 | 490 | 320 |
| Buffalo | 12 | 5 | 0 | .706 | 481 | 365 |
| Miami | 7 | 10 | 0 | .412 | 347 | 424 |
| New York | 3 | 14 | 0 | .176 | 300 | 503 |
NFL News

Jaguars eye balanced rushing attack after Etienne departure
Travis Etienne Jr. signed elsewhere in free agency, leaving a hole for Bhayshul Tuten and Chris Rodriguez Jr.
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What's the Seahawks' plan at running back in 2026?
Kenneth Walker's departure leaves a hole in a backfield already weakened by Zach Charbonnet's injury.
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After 6-11 season, did Chiefs do enough in free agency?
The Chiefs hope their free agent class can make a bigger impact than last year's underwhelming acquisitions.
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