If you're an ESPN Fantasy Rugby manager, you may have highlighted this fixture as this weekend's big, point-scoring opportunity. Look no further than Ireland wingers Jacob Stockdale and Keith Earls to bag some points, while Sexton is at No. 10 would be a smart selection at kicker against Italy.

Remember to check your scores and see how you've got on so far this weekend.

Italy have made five changes to their starting XV, the most significant is in the back row where Braam Steyn shifts to No. 8 in place of captain Sergio Parisse, who is out with concussion.

Maxime Mbanda steps in as flanker and Jimmy Tuivaiti is also in the back row as he replaces Sebastian Negri, who has failed to overcome illness.

Leonardo Ghiraldini is named as captain in Parisse's absence while Federico Ruzza comes in at lock after impressing from the bench against Wales two weeks ago.

Andrea Lovotti is preferred at tighthead prop and Benetton No. 9 Tito Tabaldi returns in place of Guglielmo Palazzini at scrum-half.

Ireland have made four changes from the side that defeated Scotland in Edinburgh two weeks ago but have stuck with a strong team for the clash against Italy.

Sean Cronin receives his first Six Nations start at hooker in place of Rory Best, who is rested, while Dave Kilcoyne also starts in the front row.

Jordi Murphy is included in the back row and Ultan Dillane will make his Six Nations debut at lock.

Jonny Sexton was an injury worry during the week after being forced off during the Scotland match but is fit enough to start at No. 10.