| MLB First Round Draft Picks - Boston Red Sox | ||||
| SEASON | PLAYER | POS | SCHOOL/HOMETOWN | PICK |
| 2016 | Jason Groome | LHP | Barnegat (New Jersey) High School | 12 |
| 2015 | Andrew Benintendi | OF | Arkansas | 7 |
| 2014 | Michael Chavis | 3B | Sprayberry HS, Marietta, Ga. | 26 |
| 2013 | Trey Ball | LHP | New Castle (Ind.) High School | 7 |
| 2012 | Brian Johnson | LHP | Florida | 31 |
| 2012 | Deven Marrero | SS | Arizona State | 24 |
| 2011 | Blake Swihart | C | Cleveland High School | 26 |
| 2011 | Matt Barnes | RHP | Connecticut | 19 |
| 2010 | Anthony Ranaudo | RHP | Louisiana State University | 39 |
| 2010 | Bryce Brentz | OF | Middle Tennessee State | 36 |
| 2010 | Kolbrin Vitek | 2B | Ball State | 20 |
| 2009 | Reymond Fuentes | OF | Fernando Callejo HS, Manati, PR | 28 |
| 2008 | Casey Kelly | SS | Sarasota (Fla.) H.S. | 30 |
| 2006 | Daniel Bard | RHP | North Carolina | 28 |
| 2006 | Jason Place | OF | Wren HS (Easley, H.S.) | 27 |
| 2005 | Craig Hansen | RHP | St. Johns | 26 |
| 2005 | Jacoby Ellsbury | CF | Oregon St | 23 |
| 2003 | David Murphy | OF | Baylor U. | 17 |
| 2000 | Phil Dumatrait | LHP | Bakersfield, CA | 22 |
| 1999 | Rick Asadoorian | OF | Whitinsville, MA | 17 |
| 1998 | Jeffrey Everett | SS | U. of South Carolina | 12 |
| 1997 | John Curtice | LHP | Chesapeake, VA | 17 |
| 1996 | Josh Garrett | RHP | Richland, IN | 26 |
| 1995 | Corey Jenkins | OF | Columbia, SC | 24 |
| 1995 | Andy Yount | RHP | Kingwood, TX | 15 |
| 1994 | Nomar Garciaparra | SS | Georgia Tech | 12 |
| 1993 | Trot Nixon | OF | Wilmington, NC | 7 |
| 1991 | Aaron Sele | RHP | Washington State U | 23 |
| 1989 | Maurice Vaughn | 1B | Seton Hall U | 23 |
| 1989 | Greg Blosser | OF | Sarasota, FL | 16 |
| 1988 | Tom Fischer | LHP | U of Wisconsin | 12 |
| 1987 | Reggie Harris | RHP | Waynesboro, VA | 26 |
| 1986 | *-Greg McMurtry | OF | Brockton, MA | 14 |
| 1985 | Dan Gabriele | RHP | Walled Lake, MI | 21 |
| 1984 | John Marzano | C | Temple U | 14 |
| 1983 | Roger Clemens | RHP | U of Texas | 19 |
| 1982 | Jeff Ledbetter | 1B-OF | Florida State U | 26 |
| 1982 | Rob Parkins | RHP | Cerritos, CA | 18 |
| 1982 | Sam Horn | 1B | San Diego, CA | 16 |
| 1981 | Kevin Burrell | C | Poway, CA | 25 |
| 1981 | Steve Lyons | OF-SS | Oregon State U | 19 |
| 1977 | Andrew Madden | RHP | New Hartford, NY | 13 |
| 1976 | Bruce Hurst | LHP | St. George, UT | 22 |
| 1975 | Otis Foster | 1B | High Point College | 15 |
| 1974 | Eddie Ford | SS | U of South Carolina | 20 |
| 1973 | Ted Cox | SS | Midwest City, OK | 17 |
| 1972 | Joel Bishop | SS | Sacramento, CA | 16 |
| 1971 | Jim Rice | OF | Anderson, SC | 15 |
| 1970 | *-Jimmy Hacker | SS | Temple, TX | 16 |
| 1969 | Noel Jenke | OF | U of Minnesota | 13 |
| 1968 | Tom Maggard | OF-C | Norwalk, CA | 20 |
| 1967 | Mike Garman | RHP | Caldwell, ID | 3 |
| 1966 | Ken Brett | LHP | El Segundo, CA | 4 |
| 1965 | Billy Conigliaro | OF | Swampscott, MA | 5 |