PHOENIX -- David Peralta, A.J. Pollock and Jake Lamb hit back-to-back-to-back home runs for Arizona in the first inning Friday night against Washington star Max Scherzer, the first time the Diamondbacks have started a game with three straight homers.
The first-inning feat was the first in the majors since Baltimore did it against Texas on May 10, 2012. It was the first time in Nationals history (2005 to present) that an opposing team has hit back-to-back-to-back home runs.
The Diamondbacks last hit three straight homers on Aug. 11, 2010, when they had four in a row at Milwaukee.
It was the most runs allowed by Scherzer in a first inning since July 2, 2011, against San Francisco, when he gave up five.
"I had four pitches today. I was using them. They beat me," Scherzer said. "I just couldn't get the ball exactly where I wanted it. When you do that against this type of ballclub and these types of hitters, they are really good and they make you pay."
Scherzer's five runs allowed tied for the most he has given up in a start this season, and the five innings tied for his shortest outing of the season.
Arizona sent nine batters to the plate in the four-run first, and the Diamondbacks made it 5-0 in the second on Lamb's RBI double.
Scherzer had allowed just one home run in 34 2/3 innings over five starts before he surrendered the three home runs on his first 10 pitches. He was tagged for three homers in a game for the first time since May 6, 2016, against the Chicago Cubs, when he allowed four.
"I don't think I have ever seen a game starting off with three homers. Max hadn't seen it, either," Nationals manager Dusty Baker said.
Arizona went on to win 6-5 on Brandon Drury's walk-off, bases-loaded single in the ninth. It was the Diamondbacks' seventh walk-off win over the season, tied for the most in the majors, according to ESPN Stats & Info.
The Associated Press contributed to this report.