The Minnesota Twins will open their AL Central title defense without closer Jhoan Duran, who has a moderate oblique strain.
Duran, reliever Caleb Thielbar and starting pitcher Anthony DeSclafani all are expected to open the season on the injured list.
Thielbar has a hamstring injury, while DeSclafani is dealing with an elbow issue.
DeSclafani is scheduled to see Dr. Keith Meister to be further evaluated, according to Twins president of baseball operations Derek Falvey.
Duran had 27 saves last season for the Twins.
The Associated Press contributed to this report.