Find out who is missing through injury, who's in a race against time to prove their fitness and who has been ruled out through suspension for the next round of Premier League fixtures.
And as you plan your fantasy team for the next gameweek, check out the predicted XIs for all 20 clubs.
Positions: Goalkeeper (GK), Defender (D), Left-back (LB), Right-back (RB), Centre-back (CB), Midfielder (M), Defensive midfield (DM), Central midfield (CM), Left midfield (LM), Right midfield (RM), Attacking midfield (AM), Left winger (LW), Right winger (RW), Forward (F), Left forward (FWL), Right forward (FWR), Striker (ST)
(All predicted XIs and injury news powered by Rotowire, subject to updates.)
Brentford v AFC Bournemouth
Gtech Community Stadium
Saturday, 10 a.m. ET / 3 p.m. UK
Latest Brentford team news
Expected Lineup:
GK Mark Flekken
LB Sepp van den Berg | CB Nathan Collins | CB Ethan Pinnock | RB Mads Roerslev
DM Vitaly Janelt | DM Christian Nørgaard
LW Keane Lewis-Potter | AM Mikkel Damsgaard | RW Bryan Mbeumo
ST Yoane Wissa
Injury/suspension updates:
Kristoffer Ajer, D, foot, DOUBT
Josh Dasilva, M, knee, OUT, estimated return Jan. 14
Rico Henry, M/D, knee, OUT, estimated return Nov. 9
Aaron Hickey, M/D, hamstring, OUT, estimated return May. 18
Igor Thiago, F, knee, OUT, estimated return Nov. 23
Gustavo Nunes, F/M, back, OUT, estimated return Nov. 23
Latest AFC Bournemouth team news
Expected Lineup:
GK Mark Travers
LB Milos Kerkez | CB Marcos Senesi | CB Illia Zabarnyi | RB Adam Smith
DM Ryan Christie | DM Lewis Cook
LW Marcus Tavernier | AM Justin Kluivert | RW Antoine Semenyo
ST Evanilson
Injury/suspension updates:
Kepa Arrizabalaga, G, thigh, DOUBT
Dango Ouattara, F/M, undisclosed, OUT, estimated return Nov. 23
Alex Scott, M, knee, OUT, estimated return Dec. 21
Luis Sinisterra, F/M, hamstring, OUT, estimated return Nov. 23
Crystal Palace v Fulham
Selhurst Park
Saturday, 10 a.m. ET / 3 p.m. UK
Latest Crystal Palace team news
Expected Lineup:
GK Dean Henderson
CB Trevoh Chalobah | CB Marc Guéhi | CB Maxence Lacroix
LM Tyrick Mitchell | CM Cheick Doucoure | CM Jeffrey Schlupp | RM Daniel Muñoz
AM Daichi Kamada | AM Ismaïla Sarr
ST Jean-Philippe Mateta
Injury/suspension updates:
Eberechi Eze, F/M, hamstring, OUT, estimated return Nov. 23
Matheus França, F/M, groin, OUT, estimated return Nov. 23
Will Hughes, M, suspension, due back Nov. 23
Jefferson Lerma, M, hamstring, OUT, estimated return Nov. 23
Eddie Nketiah, F, hamstring, DOUBT
Chadi Riad, D, knee, OUT, estimated return Nov. 23
Chris Richards, D, hamstring, DOUBT
Joel Ward, D, undisclosed, DOUBT
Adam Wharton, M, groin, OUT, estimated return Dec. 3
Latest Fulham team news
Expected Lineup:
GK Bernd Leno
LB Antonee Robinson | CB Joachim Andersen | CB Calvin Bassey | RB Kenny Tete
DM Sander Berge | DM Andreas Pereira
LW Alex Iwobi | AM Emile Smith Rowe | RW Reiss Nelson
ST Raúl Jiménez
Injury/suspension updates:
Sasa Lukic, M, shoulder, OUT, estimated return Nov. 23
Carlos Vinícius, F, undisclosed, DOUBT
West Ham United v Everton
London Stadium
Saturday, 10 a.m. ET / 3 p.m. UK
Latest West Ham United team news
Expected Lineup:
GK Lukasz Fabianski
CB Max Kilman | CB Konstantinos Mavropanos | CB Jean-Clair Todibo
LM Emerson | CM Tomás Soucek | CM Guido Rodríguez | RM Aaron Wan-Bissaka
AM Jarrod Bowen | AM Lucas Paquetá
ST Michail Antonio
Injury/suspension updates:
Edson Álvarez, M, suspension, due back Nov. 30
Niclas Füllkrug, F, calf, OUT, estimated return Nov. 30
Mohammed Kudus, F/M, suspension, due back Dec. 3
Tomás Soucek, M, illness, DOUBT
Latest Everton team news
Expected Lineup:
GK Jordan Pickford
LB Vitaliy Mykolenko | CB Jarrad Branthwaite | CB James Tarkowski | RB Ashley Young
DM Idrissa Gueye | DM Orel Mangala
LW Iliman Ndiaye | AM Dwight McNeil | RW Jesper Lindstrom
ST Dominic Calvert-Lewin
Injury/suspension updates:
Armando Broja, F, ankle, OUT, estimated return Nov. 23
Seamus Coleman, D, hamstring, OUT, estimated return Nov. 23
Abdoulaye Doucouré, F/M, undisclosed, DOUBT
James Garner, M, back, OUT, estimated return Dec. 1
Tim Iroegbunam, M, foot, OUT, estimated return Nov. 23
Iliman Ndiaye, F/M, undisclosed, DOUBT
Youssef Chermiti, F, foot, OUT, estimated return Nov. 23
Wolverhampton Wanderers v Southampton
Molineux Stadium
Saturday, 10 a.m. ET / 3 p.m. UK
Latest Wolverhampton Wanderers team news
Expected Lineup:
GK Sam Johnstone
CB Santiago Bueno | CB Craig Dawson | CB Toti Gomes
LM Rayan Aït-Nouri | CM Tommy Doyle | CM João Gomes | RM Nélson Semedo
AM Matheus Cunha | AM Mario Lemina
ST Jørgen Strand Larsen
Injury/suspension updates:
Enso Gonzalez, F/M, knee, OUT, estimated return May. 3
Hwang Hee-Chan, F, ankle, DOUBT
Sam Johnstone, G, groin, DOUBT
Sasa Kalajdzic, F, knee, OUT, estimated return Jan. 15
Bastien Meupiyou, M/D, undisclosed, DOUBT
Yerson Mosquera, D, knee, OUT, estimated return Aug. 15
Boubacar Traoré, M, knee, OUT, estimated return Jan. 15
Latest Southampton team news
Expected Lineup:
GK Aaron Ramsdale
LB Ryan Manning | CB Jan Bednarek | CB Taylor Harwood-Bellis | CB Jack Stephens | RB Kyle Walker-Peters
CM Joe Aribo | CM Flynn Downes | CM Mateus Fernandes
ST Cameron Archer | ST Adam Armstrong
Injury/suspension updates:
Gavin Bazunu, G, achilles, OUT, estimated return Jan. 11
Ryan Fraser, F/M, undisclosed, OUT, estimated return Nov. 24
Adam Lallana, M, groin, DOUBT
William Smallbone, M, hamstring, OUT, estimated return Nov. 24
Ross Stewart, F, calf, OUT, estimated return Nov. 24
Brighton & Hove Albion v Manchester City
American Express Stadium
Saturday, 12:30 p.m. ET / 5:30 p.m. UK
Latest Brighton & Hove Albion team news
Expected Lineup:
GK Bart Verbruggen
LB Pervis Estupiñán | CB Igor Julio | CB Jan Paul van Hecke | RB Joël Veltman
LM Kaoru Mitoma | CM Carlos Baleba | CM Jack Hinshelwood | RM Ferdi Kadioglu
ST Georginio Rutter | ST Danny Welbeck
Injury/suspension updates:
Yasin Ayari, M, undisclosed, DOUBT
Carlos Baleba, M, knee, DOUBT
Lewis Dunk, D, calf, DOUBT
João Pedro, F/M, ankle, DOUBT
Solly March, F/M, knee, OUT, estimated return Nov. 23
James Milner, M/D, hamstring, OUT, estimated return Nov. 23
Yankuba Minteh, F, groin, DOUBT
Matt O'Riley, M, ankle, DOUBT
Adam Webster, D, hamstring, OUT, estimated return Nov. 23
Latest Manchester City team news
Expected Lineup:
GK Ederson
LB Josko Gvardiol | CB Manuel Akanji | CB Nathan Aké | RB Kyle Walker
DM Ilkay Gündogan
LM Jérémy Doku | CM Phil Foden | CM Bernardo Silva | RM Savinho
ST Erling Haaland
Injury/suspension updates:
Oscar Bobb, F/M, leg, OUT, estimated return Nov. 30
Rúben Dias, D, undisclosed, OUT, estimated return Nov. 23
Jack Grealish, F/M, undisclosed, OUT, estimated return Nov. 23
Rodri, M, knee, OUT, estimated return Jul. 1
John Stones, D, undisclosed, OUT, estimated return Nov. 23
Liverpool v Aston Villa
Anfield
Saturday, 3 p.m. ET / 8 p.m. UK
Latest Liverpool team news
Expected Lineup:
GK Caoimhín Kelleher
LB Andrew Robertson | CB Ibrahima Konaté | CB Virgil van Dijk | RB Trent Alexander-Arnold
DM Ryan Gravenberch | DM Alexis Mac Allister
LW Luis Díaz | AM Dominik Szoboszlai | RW Mohamed Salah
ST Darwin Núñez
Injury/suspension updates:
Alisson Becker, G, hamstring, OUT, estimated return Nov. 24
Federico Chiesa, F/M, undisclosed, OUT, estimated return Nov. 24
Harvey Elliott, F/M, foot, OUT, estimated return Nov. 24
Diogo Jota, F, upper body, OUT, estimated return Nov. 24
Latest Aston Villa team news
Expected Lineup:
GK Emiliano Martínez
LB Lucas Digne | CB Diego Carlos | CB Pau Torres | RB Ezri Konsa
DM Amadou Onana | DM Youri Tielemans
LW Jacob Ramsey | AM Morgan Rogers | RW John McGinn
ST Ollie Watkins
Injury/suspension updates:
Ross Barkley, M, undisclosed, OUT, estimated return Nov. 23
Matty Cash, D, calf, OUT, estimated return Nov. 23
Manchester United v Leicester City
Old Trafford
Sunday, 9 a.m. ET / 2 p.m. UK
Latest Manchester United team news
Expected Lineup:
GK André Onana
LB Noussair Mazraoui | CB Matthijs de Ligt | CB Lisandro Martínez | RB Diogo Dalot
DM Manuel Ugarte | DM Casemiro
LW Marcus Rashford | AM Bruno Fernandes | RW Alejandro Garnacho
ST Rasmus Højlund
Injury/suspension updates:
Toby Collyer, M, undisclosed, DOUBT
Harry Maguire, D, calf, OUT, estimated return Nov. 24
Kobbie Mainoo, M, knee, DOUBT
Tyrell Malacia, D, knee, OUT, estimated return Dec. 1
Luke Shaw, D, calf, OUT, estimated return Nov. 24
Leny Yoro, D, foot, OUT, estimated return Nov. 28
Latest Leicester City team news
Expected Lineup:
GK Mads Hermansen
LB Victor Kristiansen | CB Wout Faes | CB Jannik Vestergaard | RB James Justin
DM Wilfred Ndidi | DM Harry Winks
LW Stephy Mavididi | AM Facundo Buonanotte | RW Fatawu Issahaku
ST Jamie Vardy
Injury/suspension updates:
Hamza Choudhury, M, shoulder, OUT, estimated return Nov. 23
Patson Daka, F, ankle, DOUBT
Jakub Stolarczyk, G, ankle, OUT, estimated return Nov. 23
Nottingham Forest v Newcastle United
The City Ground
Sunday, 9 a.m. ET / 2 p.m. UK
Latest Nottingham Forest team news
Expected Lineup:
GK Matz Sels
LB Álex Moreno | CB Murillo | CB Nikola Milenkovic | RB Ola Aina
DM Nicolás Domínguez | DM Ryan Yates
LW Callum Hudson-Odoi | AM Morgan Gibbs-White | RW Anthony Elanga
ST Chris Wood
Injury/suspension updates:
Danilo Oliveira, M, ankle, OUT, estimated return Dec. 21
Ibrahim Sangaré, M, thigh, OUT, estimated return Nov. 23
James Ward-Prowse, M, not injury related, DOUBT
Latest Newcastle United team news
Expected Lineup:
GK Nick Pope
LB Lewis Hall | CB Dan Burn | CB Fabian Schär | RB Valentino Livramento
CM Bruno Guimaraes | CM Sandro Tonali | CM Joe Willock
FWL Joelinton | ST Alexander Isak | FWR Anthony Gordon
Injury/suspension updates:
Sven Botman, D, knee, OUT, estimated return Dec. 4
Jamaal Lascelles, D, knee, OUT, estimated return Jan. 15
Jacob Murphy, F/M, hamstring, DOUBT
Matt Targett, D, not injury related, OUT, estimated return Nov. 25
Kieran Trippier, D, hamstring, OUT, estimated return Nov. 25
Callum Wilson, F, back, OUT, estimated return Nov. 25
Tottenham Hotspur v Ipswich Town
Tottenham Hotspur Stadium
Sunday, 9 a.m. ET / 2 p.m. UK
Latest Tottenham Hotspur team news
Expected Lineup:
GK Guglielmo Vicario
LB Destiny Udogie | CB Radu Dragusin | CB Cristian Romero | RB Pedro Porro
CM Dejan Kulusevski | CM Rodrigo Bentancur | CM Pape Matar Sarr
FWL Son Heung-Min | ST Dominic Solanke | FWR Brennan Johnson
Injury/suspension updates:
Richarlison, F, hamstring, OUT, estimated return Nov. 28
Mikey Moore, F/M, illness, OUT, estimated return Nov. 23
Wilson Odobert, F/M, hamstring, OUT, estimated return Nov. 23
Cristian Romero, D, foot, DOUBT
Djed Spence, M/D, groin, OUT, estimated return Nov. 23
Micky van de Ven, D, hamstring, OUT, estimated return Nov. 23
Timo Werner, F/M, groin, OUT, estimated return Nov. 23
Latest Ipswich Town team news
Expected Lineup:
GK Aro Muric
LB Leif Davis | CB Cameron Burgess | CB Dara O'Shea | RB Ben Johnson
DM Jens Cajuste | DM Sam Morsy
AM Conor Chaplin | RW Omari Hutchinson
ST Liam Delap
Injury/suspension updates:
Jacob Greaves, D, undisclosed, OUT, estimated return Nov. 24
Chiedozie Ogbene, F/M, achilles, OUT, estimated return May. 3
Kalvin Phillips, M, suspension, due back Nov. 24
Cieran Slicker, G, undisclosed, OUT, estimated return Nov. 24
Axel Tuanzebe, D, hand, OUT, estimated return Nov. 24
Chelsea v Arsenal
Stamford Bridge
Sunday, 11:30 a.m. ET / 4:30 p.m. UK
Latest Chelsea team news
Expected Lineup:
GK Robert Sánchez
LB Marc Cucurella | CB Levi Colwill | CB Wesley Fofana | RB Reece James
DM Moisés Caicedo | DM Enzo Fernández
LW Pedro Neto | AM Cole Palmer | RW Noni Madueke
ST Nicolas Jackson
Injury/suspension updates:
Cole Palmer, F/M, knee, DOUBT
Jadon Sancho, F/M, illness, DOUBT
Latest Arsenal team news
Expected Lineup:
GK David Raya
LB Jurriën Timber | CB Gabriel Magalhaes | CB William Saliba | RB Ben White
DM Declan Rice | DM Thomas Partey
LW Gabriel Martinelli | AM Leandro Trossard | RW Bukayo Saka
ST Kai Havertz
Injury/suspension updates:
Riccardo Calafiori, D, knee, OUT, estimated return Nov. 23
Kai Havertz, F/M, forehead, DOUBT
Declan Rice, M, toe, DOUBT
Kieran Tierney, D, hamstring, OUT, estimated return Nov. 23
Takehiro Tomiyasu, D, knee, OUT, estimated return Nov. 23