Here are the betting lines for every first-round game from the Westgate Las Vegas SuperBook.
For help with every selection, be sure to check out PickCenter, which has projections for every NCAA tournament game.
Lines as of Friday morning at 9:00 a.m. ET.
South Region
No. 1 Virginia Cavaliers (-21.5) vs. No. 16 UMBC Retrievers
No. 8 Creighton Bluejays (-1) vs. No. 9 Kansas State Wildcats
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No. 7 Nevada Wolf Pack vs. No. 10 Texas Longhorns (-1.5)
No. 2 Cincinnati Bearcats (-14) vs. No. 15 Georgia State Panthers
Midwest Region
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No. 5 Clemson Tigers (-5) vs. No. 12 New Mexico State Aggies
No. 4 Auburn Tigers (-9.5) vs. No. 13 Charleston Cougars
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No. 6 TCU Horned Frogs (-5) vs. No. 11 Syracuse Orange
No. 3 Michigan State Spartans (-14) vs. No. 14 Bucknell Bison
East Region
No. 5 West Virginia Mountaineers (-10.5) vs. No. 12 Murray State Racers
No. 4 Wichita State Shockers (-12) vs. No. 13 Marshall Thundering Herd
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No. 7 Arkansas Razorbacks vs. No. 10 Butler Bulldogs (-1.5)
No. 2 Purdue Boilermakers (-20.5) vs. No. 15 CS Fullerton Titans
West Region
No. 1 Xavier Musketeers (-19.5) vs. No. 16 Texas Southern
No. 8 Missouri Tigers vs. No. 9 Florida State Seminoles (-2)
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No. 7 Texas A&M Aggies (-3) vs. No. 10 Providence Friars
No. 2 North Carolina Tar Heels (-20.5) vs. No. 15 Lipscomb Bisons