The Toronto Blue Jays activated right-hander Yariel Rodriguez to start Friday's series opener at Cleveland.
Rodriguez, 27, had been on the 15-day injured list since April 30 with thoracic spine inflammation.
Rodriguez (0-1, 4.11 ERA) made his MLB debut on April 13 and has never faced the Guardians.
The Blue Jays optioned right-hander Ryan Burr to Triple-A Buffalo in a corresponding transaction.