NFL Nation answers the biggest fantasy questions -- provided by ESPN fantasy football analyst Mike Clay -- across the league for Week 1.
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Buffalo Bills
How many touches should we expect for Devin Singletary?
There's no precedent for Singletary in his first NFL game, but I'd expect anywhere between eight and 15 combined touches for the running back. That number could increase or decrease depending on who has the hot hand among him, Frank Gore and T.J. Yeldon. -- Marcel Louis-Jacques
Miami Dolphins
How much of a role will Preston Williams play in his first pro game?
I wouldn't count on much from Williams in his first game, but he might be a deep sleeper to watch after the Kenny Stills trade. Williams is the Dolphins' No. 4 receiver, but I don't expect Jakeem Grant to be a full-time player, and early success could carve out a bigger role for the rookie. Williams' early role could be as a red zone and situational third-down threat, getting three or four targets per game. -- Cameron Wolfe
New England Patriots
Who will operate as the team's No. 3 receiver behind Julian Edelman and Josh Gordon?