Boston Red Sox pitcher Eduardo Rodriguez left Saturday's 6-2 win against the Toronto Blue Jays in the sixth inning because of a sprained right ankle.
Rodriguez was cruising against the Blue Jays when he ran to cover first base on a grounder by Toronto's Lourdes Gurriel.
First baseman Blake Swihart's throw was behind Rodriguez, who leaped to catch the throw and also to avoid a sliding Gurriel at the bag. As he landed, Rodriguez's right ankle appeared to bend awkwardly.
Trainers from both teams tended to Rodriguez and Gurriel, who initially stayed in the game. Rodriguez, who was replaced by right-hander Heath Hembree, had pitched 5 1/3 scoreless innings against Toronto.
X-rays were negative.
"It looks bad, but we'll see,'' manager Alex Cora said. "He's moving around, which is encouraging.''
Blue Jays center fielder Kevin Pillar left the game with a right clavicle injury after making a diving catch on Brock Holt's shallow fly, on which he rolled on the field before throwing to second for an inning-ending double play.
"He's at the hospital getting checked right now,'' Jays manager John Gibbons said.
Information from The Associated Press was used in this report.