Barcelona will be without more than half a dozen first-team players for Wednesday's Champions League game against PSV Eindhoven after Luis Suarez and Arthur were added to their injury list.
Suarez will be out for two weeks after aggravating a knee problem and is also set to miss the games against Villarreal, Cultural Leonesa and Espanyol.
However, the former Liverpool forward should be back for Tottenham's Champions League visit to the Camp Nou on Dec. 12.
Midfielder Arthur will sit out the PSV game with an abdominal injury, but Barca hope he will be fit to face Villarreal on Sunday.
Suarez and Arthur join Rafinha and Sergi Roberto on the sidelines. Rafinha is likely to miss the rest of the season with a ligament problem, while Roberto is sidelined for around a month with a hamstring strain.
Jasper Cillessen, Sergi Samper and Thomas Vermaelen are also unavailable, but Philippe Coutinho and Ivan Rakitic have recovered from recent knocks and will make the trip to Eindhoven.
Coach Ernesto Valverde has had to call up a number of youngsters to fill in for the injured players. Goalkeepers Inaki Pena and Jokin Ezkieta will travel, along with Carles Alena, Riqui Puig, Juan Miranda and Chumi.
Barca have sealed their place in the Champions League round of 16 with two games to spare, and victory in Eindhoven would see them win their group.