Arsenal manager Mikel Arteta said his side's defeat to Bournemouth on Saturday was "an accident waiting to happen" after William Saliba was sent off in the first half.
Bournemouth won 2-0 thanks to goals from Ryan Christie and Justin Kluivert after Saliba was shown a red card for a challenge on Evanilson after 30 minutes as Arsenal suffered their first defeat of the campaign.
It is the third time this season Arsenal have been forced to finish a match with 10 players, leaving Arteta frustrated that his side's lack of discipline cost them points.
"We are obviously very disappointed with the result and gutted because we have to play again in that context," he said. "This time was even more difficult than the previous two we faced this season.
"Playing for 65 or 68 minutes with 10 men at this level is just an impossible task. It's an accident waiting to happen, not to get the points.
"I cannot fault the team for their effort, their commitment, how intelligent they are to play in the way that we have to do it."
Declan Rice was sent off in Arsenal's 1-1 draw at home to Brighton earlier in the season, while Leandro Trossard was also shown red in the 2-2 draw against title rivals Manchester City.
Arsenal host Shakhtar Donetsk in the Champions League on Tuesday.