Find out who is missing through injury, who's in a race against time to prove their fitness and who has been ruled out through suspension for the next round of LaLiga fixtures.
And as you plan your fantasy team for the next gameweek, check out the predicted XIs for all 20 clubs.
Positions: Goalkeeper (GK), Defender (D), Left-back (LB), Right-back (RB), Centre-back (CB), Midfielder (M), Defensive midfield (DM), Central midfield (CM), Left midfield (LM), Right midfield (RM), Attacking midfield (AM), Left winger (LW), Right winger (RW), Forward (F), Left forward (FWL), Right forward (FWR), Striker (ST)
(All predicted XIs and injury news powered by Rotowire and subject to updates.)
Mallorca v Valencia
Estadi Mallorca Son Moix, Mallorca
Friday, 3 p.m. ET / 8 p.m. UK
Latest Mallorca team news
Expected Lineup:
GK Dominik Greif
LB Johan Mojica | CB Antonio Raíllo | CB Martin Valjent | RB Mateu Morey
LM Dani Rodríguez | CM Samú Costa | CM Sergi Darder | CM Manu Morlanes | RM Robert Navarro
ST Cyle Larin
Injury/suspension updates:
Takuma Asano, F, strain, OUT, estimated return Dec. 3
Vedat Muriqi, F, suspension, due back Dec. 3
Abdón Prats, F, hamstring, DOUBT
Latest Valencia team news
Expected Lineup:
GK Giorgi Mamardashvili
LB José Gayà | CB Yarek Gasiorowski | CB Cristhian Mosquera | CB Cesar Tarrega | RB Dimitri Foulquier
LM Diego Lopez | CM Pepelu | CM Javier Guerra | RM Luis Rioja
ST Hugo Duro
Injury/suspension updates:
Max Caufriez, D, foot, OUT, estimated return Dec. 7
Thierry Correia, D, knee, OUT, estimated return Jul. 1
Mouctar Diakhaby, D, knee, OUT, estimated return Dec. 7
Rafa Mir, F, quadriceps, OUT, estimated return Dec. 11
Barcelona v Las Palmas
Estadi Olímpic Lluís Companys, Barcelona
Saturday, 8 a.m. ET / 1 p.m. UK
Latest Barcelona team news
Expected Lineup:
GK Iñaki Peña
LB Hector Fort | CB Iñigo Martínez | CB Pau Cubarsí | RB Jules Koundé
DM Frenkie de Jong | DM Pedri
LW Raphinha | AM Dani Olmo | RW Gavi
ST Robert Lewandowski
Injury/suspension updates:
Ronald Araújo, D, hamstring, OUT, estimated return Nov. 30
Marc Bernal, M/D, knee, OUT, estimated return Sep. 1
Marc Casadó, M, suspension, due back Dec. 3
Andreas Christensen, D, achilles, OUT, estimated return Jan. 19
Ansu Fati, F, hamstring, OUT, estimated return Dec. 11
Marc-André ter Stegen, G, knee, OUT, estimated return Apr. 6
Ferran Torres, F, hamstring, OUT, estimated return Nov. 30
Lamine Yamal, F, ankle, DOUBT
Latest Las Palmas team news
Expected Lineup:
GK Jasper Cillessen
LB Álex Muñoz | CB Scott McKenna | CB Álex Suárez | RB Viti
DM José Campaña | DM Dário Essugo
LW Alberto Moleiro | AM Kirian Rodríguez | RW Sandro
ST Fábio Silva
Injury/suspension updates:
Marvin, M/D, hamstring, DOUBT
Alavés v Leganés
Mendizorroza, Vitoria-Gasteiz
Saturday, 10:15 a.m. ET / 3:15 p.m. UK
Latest Alavés team news
Expected Lineup:
GK Antonio Sivera
LB Moussa Diarra | CB Abdel Abqar | CB Santiago Mouriño | RB Nahuel Tenaglia
DM Antonio Blanco | DM Ander Guevara
LW Carlos Martín | AM Jon Guridi | RW Carlos Vicente
ST Enrique García
Injury/suspension updates:
Hugo Novoa, M, abdomen, OUT, estimated return Dec. 8
Carlos Benavídez, M, hamstring, OUT, estimated return Dec. 8
Manu Sánchez, D, suspension, due back Dec. 8
Latest Leganés team news
Expected Lineup:
GK Marko Dmitrovic
LB Javi Hernández | CB Sergio González | CB Matija Nastasic | RB Adrià Altimira
DM Renato Tapia
CM Seydouba Cissé | CM Yvan Neyou
FWL Munir El Haddadi | ST Miguel De la Fuente | FWR Juan Cruz
Injury/suspension updates:
Enric Franquesa, D, knee, OUT, estimated return Sep. 1
Espanyol v Celta Vigo
RCDE Stadium, Barcelona
Saturday, 12:30 p.m. ET / 5:30 p.m. UK
Latest Espanyol team news
Expected Lineup:
GK Joan García
LB Brian Oliván | CB Leandro Cabrera | CB Marash Kumbulla | RB Omar El Hilali
LM Jofre Carreras | CM Alex Král | CM Pol Lozano | RM Álvaro Tejero
ST Alejo Veliz | ST Javi Puado
Injury/suspension updates:
Fernando Calero, D, achilles, DOUBT
Edu Exposito, M, knee, OUT, estimated return Dec. 8
José Gragera, M, illness, DOUBT
Latest Celta Vigo team news
Expected Lineup:
GK Vicente Guaita
CB Javier Rodriguez | CB Carl Starfelt | CB Marcos Alonso
LM Hugo Álvarez | CM Fran Beltrán | CM Hugo Sotelo | RM Óscar Mingueza
AM Iago Aspas | AM Jonathan Bamba
ST Anastasios Douvikas
Injury/suspension updates:
Sergio Carreira, D, ankle, DOUBT
Luca de la Torre, M, ankle, OUT, estimated return Dec. 6
Jailson, M, groin, DOUBT
Williot Swedberg, F/M, illness, DOUBT
Real Valladolid v Atlético Madrid
José Zorrilla, Valladolid
Saturday, 3 p.m. ET / 8 p.m. UK
Latest Real Valladolid team news
Expected Lineup:
GK Karl Hein
LB Lucas Rosa | CB Juma Bah | CB Cenk Özkacar | CB Javi Sánchez | RB Luis Pérez
CM Stanko Juric | CM Kike Perez
AM Raúl Moro | AM Anuar
ST Mamadou Diallo
Injury/suspension updates:
None reported
Latest Atlético Madrid team news
Expected Lineup:
GK Jan Oblak
LB Javi Galán | CB José María Giménez | CB Clément Lenglet | CB Axel Witsel | RB Marcos Llorente
CM Pablo Barrios | CM Koke
AM Antoine Griezmann | AM Samuel Lino
ST Julián Álvarez
Injury/suspension updates:
Robin Le Normand, D, concussion, OUT, estimated return Nov. 30
Thomas Lemar, M, undisclosed, OUT, estimated return Dec. 15
Nahuel Molina, M/D, thigh, OUT, estimated return Nov. 30
Villarreal v Girona
Estadio de la Cerámica, Villarreal
Sunday, 8 a.m. ET / 1 p.m. UK
Latest Villarreal team news
Expected Lineup:
GK Diego Conde
LB Sergi Cardona | CB Raúl Albiol | CB Logan Costa | RB
LM Álex Baena | CM Santi Comesaña | CM Dani Parejo | RM Yeremy Pino
ST Thierno Barry | ST Gerard Moreno
Injury/suspension updates:
Ilias Akhomach, F, knee, OUT, estimated return Jul. 1
Eric Bailly, D, shoulder, OUT, estimated return Dec. 8
, D, undisclosed, DOUBT
Juan Foyth, D, knee, OUT, estimated return Dec. 8
Pape Gueye, M, illness, DOUBT
Alfonso Pedraza, D, ankle, OUT, estimated return Dec. 15
Nicolas Pépé, F/M, thigh, OUT, estimated return Dec. 8
Ayoze Pérez, F/M, thigh, OUT, estimated return Dec. 8
Ramón Terrats, M, achilles, OUT, estimated return Dec. 15
Latest Girona team news
Expected Lineup:
GK Paulo Gazzaniga
LB Daley Blind | CB Ladislav Krejcí | CB David López | RB Arnau Martínez
DM Oriol Romeu | DM Miguel Gutiérrez
LW Bryan Gil | AM Donny van de Beek | RW Yáser Asprilla
ST Bojan Miovski
Injury/suspension updates:
Jastin García, F/M, shoulder, OUT, estimated return Dec. 22
Yangel Herrera, M, calf, OUT, estimated return Dec. 7
Portu, F/M, ankle, OUT, estimated return Dec. 1
Gabriel Misehouy, M, hamstring, OUT, estimated return Dec. 10
Donny van de Beek, M, illness, OUT, estimated return Dec. 1
Real Madrid v Getafe
Santiago Bernabéu, Madrid
Sunday, 10:15 a.m. ET / 3:15 p.m. UK
Latest Real Madrid team news
Expected Lineup:
GK Thibaut Courtois
LB Fran García | CB Raul Asencio | CB Antonio Rüdiger | RB Federico Valverde
DM Eduardo Camavinga
CM Jude Bellingham | CM Luka Modric
FWL Kylian Mbappé | ST Endrick | FWR Arda Güler
Injury/suspension updates:
David Alaba, D, knee, OUT, estimated return Dec. 1
Eduardo Camavinga, M, thigh, OUT, estimated return Dec. 22
Dani Carvajal, D, knee, OUT, estimated return Aug. 1
Vinícius Jr., F, thigh, OUT, estimated return Dec. 1
Éder Militão, D, knee, OUT, estimated return Aug. 1
Rodrygo, F/M, hamstring, OUT, estimated return Dec. 1
Aurélien Tchouaméni, M, ankle, OUT, estimated return Dec. 1
Latest Getafe team news
Expected Lineup:
GK David Soria
LB Diego Rico | CB Omar Alderete | CB Domingos Duarte | RB Allan Nyom
LM Álex Sola | CM Mauro Arambarri | CM Luis Milla | RM Carles Pérez
ST Álvaro Rodríguez | ST Christantus Uche
Injury/suspension updates:
Carles Aleñá, M, undisclosed, DOUBT
Djené, M/D, suspension, due back Dec. 9
Borja Mayoral, F, strain, OUT, estimated return Dec. 9
Bertug Yildirim, F, suspension, due back Dec. 9
Rayo Vallecano v Athletic Club
Estadio de Vallecas, Madrid
Sunday, 12:30 p.m. ET / 5:30 p.m. UK
Latest Rayo Vallecano team news
Expected Lineup:
GK Augusto Batalla
LB Pep Chavarría | CB Florian Lejeune | CB Abdul Mumin | RB Andrei Ratiu
CM Gerard Gumbau | CM Óscar Valentín
AM Isi Palazón
FWL Álvaro García | ST Sergio Camello | FWR Jorge de Frutos
Injury/suspension updates:
Alfonso Espino, D, fracture, DOUBT
Unai López, M, suspension, due back Dec. 7
Latest Athletic Club team news
Expected Lineup:
GK Julen Agirrezabala
LB Yuri Berchiche | CB Yeray Alvarez | CB Dani Vivian | RB Óscar de Marcos
DM Mikel Jauregizar | DM Iñigo Ruiz de Galarreta
LW Nico Williams | AM Oihan Sancet | RW Iñaki Williams
ST Álvaro Djaló
Injury/suspension updates:
Beñat Prados, M, suspension, due back Dec. 4
Real Sociedad v Real Betis
Reale Arena, San Sebastián
Sunday, 3 p.m. ET / 8 p.m. UK
Latest Real Sociedad team news
Expected Lineup:
GK Álex Remiro
LB Javi López | CB Nayef Aguerd | CB Igor Zubeldia | RB Jon Aramburu
DM Martín Zubimendi
LM Sergio Gómez | CM Brais Méndez | CM Luka Sucic | RM Takefusa Kubo
ST Mikel Oyarzabal
Injury/suspension updates:
Aritz Elustondo, D, undisclosed, DOUBT
Orri Oskarsson, F, calf, OUT, estimated return Dec. 12
Hamari Traoré, D, knee, OUT, estimated return May. 4
Arsen Zakharyan, M, ankle, OUT, estimated return Dec. 8
Latest Real Betis team news
Expected Lineup:
GK Rui Silva
LB Romain Perraud | CB Natan | CB Diego Llorente | RB Youssouf Sabaly
DM Sergi Altimira | DM Carlos Guirao
LW Abde Ezzalzouli | AM Giovani Lo Celso | RW Aitor Ruibal
ST Vitor Roque
Injury/suspension updates:
Isco, F/M, leg, OUT, estimated return Dec. 7
Héctor Bellerín, D, bruise, OUT, estimated return Dec. 7
William Carvalho, M, achilles, OUT, estimated return May. 4
Johnny Cardoso, M, thigh, OUT, estimated return Dec. 7
Pablo Fornals, F/M, undisclosed, OUT, estimated return Dec. 7
Marc Roca, M, ankle, OUT, estimated return Dec. 15
Sevilla v Osasuna
Ramón Sánchez-Pizjuán, Sevilla
Monday, 3 p.m. ET / 8 p.m. UK
TBD