Find out who is missing through injury, who's in a race against time to prove their fitness and who has been ruled out through suspension for the next round of LaLiga fixtures.
And as you plan your fantasy team for the next gameweek, check out the predicted XIs for all 20 clubs.
Positions: Goalkeeper (GK), Defender (D), Left-back (LB), Right-back (RB), Centre-back (CB), Midfielder (M), Defensive midfield (DM), Central midfield (CM), Left midfield (LM), Right midfield (RM), Attacking midfield (AM), Left winger (LW), Right winger (RW), Forward (F), Left forward (FWL), Right forward (FWR), Striker (ST)
(All predicted XIs and injury news powered by Rotowire and subject to updates.)
Villarreal v Girona
Estadio de la Cerámica, Villarreal
Sunday, 8 a.m. ET / 1 p.m. UK
Latest Villarreal team news
Expected Lineup:
GK Diego Conde
LB Sergi Cardona | CB Raúl Albiol | CB Logan Costa | RB
LM Álex Baena | CM Santi Comesaña | CM Dani Parejo | RM Yeremy Pino
ST Thierno Barry | ST Gerard Moreno
Injury/suspension updates:
Ilias Akhomach, F, knee, OUT, estimated return Jul. 1
Eric Bailly, D, shoulder, OUT, estimated return Dec. 8
, D, undisclosed, DOUBT
Juan Foyth, D, knee, OUT, estimated return Dec. 8
Pape Gueye, M, illness, DOUBT
Alfonso Pedraza, D, ankle, OUT, estimated return Dec. 15
Nicolas Pépé, F/M, thigh, OUT, estimated return Dec. 8
Ayoze Pérez, F/M, thigh, OUT, estimated return Dec. 8
Ramón Terrats, M, achilles, OUT, estimated return Dec. 15
Latest Girona team news
Expected Lineup:
GK Paulo Gazzaniga
LB Daley Blind | CB Ladislav Krejcí | CB David López | RB Arnau Martínez
DM Oriol Romeu | DM Miguel Gutiérrez
LW Bryan Gil | AM Donny van de Beek | RW Yáser Asprilla
ST Bojan Miovski
Injury/suspension updates:
Jastin García, F/M, shoulder, OUT, estimated return Dec. 22
Yangel Herrera, M, calf, OUT, estimated return Dec. 7
Portu, F/M, ankle, OUT, estimated return Dec. 1
Gabriel Misehouy, M, hamstring, OUT, estimated return Dec. 10
Donny van de Beek, M, illness, OUT, estimated return Dec. 1
Real Madrid v Getafe
Santiago Bernabéu, Madrid
Sunday, 10:15 a.m. ET / 3:15 p.m. UK
Latest Real Madrid team news
Expected Lineup:
GK Thibaut Courtois
LB Fran García | CB Raul Asencio | CB Antonio Rüdiger | RB Federico Valverde
DM Eduardo Camavinga
CM Jude Bellingham | CM Luka Modric
FWL Kylian Mbappé | ST Endrick Felipe Moreira de Sousa | FWR Arda Güler
Injury/suspension updates:
David Alaba, D, knee, OUT, estimated return Dec. 22
Eduardo Camavinga, M, thigh, OUT, estimated return Dec. 22
Dani Carvajal, D, knee, OUT, estimated return Aug. 1
Vinícius Jr., F, thigh, OUT, estimated return Dec. 22
Éder Militão, D, knee, OUT, estimated return Aug. 1
Rodrygo, F/M, hamstring, DOUBT
Aurélien Tchouaméni, M, ankle, OUT, estimated return Dec. 4
Latest Getafe team news
Expected Lineup:
GK David Soria
LB Diego Rico | CB Omar Alderete | CB Domingos de Sousa Coutinho Meneses Duarte | RB Allan Nyom
LM Álex Sola | CM Mauro Arambarri | CM Luis Milla | RM Carles Pérez
ST Álvaro Rodríguez | ST Christantus Uche
Injury/suspension updates:
Carles Alena Castillo, M, undisclosed, OUT, estimated return Dec. 9
Djené, M/D, suspension, due back Dec. 9
Borja Mayoral, F, strain, OUT, estimated return Dec. 9
Bertug Yildirim, F, suspension, due back Dec. 9
Rayo Vallecano v Athletic Club
Estadio de Vallecas, Madrid
Sunday, 12:30 p.m. ET / 5:30 p.m. UK
Latest Rayo Vallecano team news
Expected Lineup:
GK Augusto Batalla
LB Pep Chavarría | CB Florian Lejeune | CB Abdul Mumin | RB Andrei Ratiu
CM Gerard Gumbau | CM Óscar Valentín
AM Isi Palazón
FWL Álvaro García | ST Sergio Camello | FWR Jorge de Frutos
Injury/suspension updates:
Alfonso Espino, D, fracture, DOUBT
Unai López, M, suspension, due back Dec. 7
Latest Athletic Club team news
Expected Lineup:
GK Julen Agirrezabala
LB Yuri Berchiche | CB Yeray Alvarez | CB Dani Vivian | RB Óscar de Marcos
DM Mikel Jauregizar | DM Iñigo Ruiz de Galarreta
LW Nico Williams | AM Oihan Sancet | RW Iñaki Williams
ST Alvaro Djalo Dias Fernandes
Injury/suspension updates:
Beñat Prados, M, suspension, due back Dec. 4
Real Sociedad v Real Betis
Reale Arena, San Sebastián
Sunday, 3 p.m. ET / 8 p.m. UK
Latest Real Sociedad team news
Expected Lineup:
GK Álex Remiro
LB Javi López | CB Nayef Aguerd | CB Igor Zubeldia | RB Jon Aramburu
DM Martín Zubimendi
LM Sergio Gómez | CM Brais Méndez | CM Luka Sucic | RM Takefusa Kubo
ST Mikel Oyarzabal
Injury/suspension updates:
Aritz Elustondo, D, undisclosed, DOUBT
Orri Oskarsson, F, calf, OUT, estimated return Dec. 12
Hamari Traoré, D, knee, OUT, estimated return May. 4
Arsen Zakharyan, M, ankle, OUT, estimated return Dec. 8
Latest Real Betis team news
Expected Lineup:
GK Rui Silva
LB Romain Perraud | CB Natan | CB Diego Llorente | RB Youssouf Sabaly
DM Sergi Altimira | DM Carlos Guirao
LW Abde Ezzalzouli | AM Giovani Lo Celso | RW Aitor Ruibal
ST Vitor Roque
Injury/suspension updates:
Isco, F/M, leg, OUT, estimated return Dec. 7
Héctor Bellerín, D, bruise, OUT, estimated return Dec. 7
William Carvalho, M, achilles, OUT, estimated return May. 4
Johnny Cardoso, M, thigh, OUT, estimated return Dec. 7
Pablo Fornals, F/M, undisclosed, OUT, estimated return Dec. 7
Marc Roca, M, ankle, OUT, estimated return Dec. 15