LSU coach Nikki Fargas announced Friday that center Faustine Aifuwa and reserve guard Dekeriya Patterson did not travel with the team to Columbus, Ohio, and will not play in Saturday's NCAA tournament opener against Central Michigan.
A school official said the two players were left behind due to a violation of team rules.
Aifuwa started 15 of 28 games this season, averaging 5.1 points and 5.0 rebounds per game. She started in LSU's final 13 games.
Yasmine Bidikuindila and Raven Farley are expected to get more time in the absence of Aifuwa, but neither has played significant minutes this season.
LSU is seeded sixth in the Spokane Bracket. The Lady Tigers are 19-9. They are just 8-8 when playing outside the Pete Maravich Assembly Center.