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Fantasy football flex rankings for Week 16

Gregory Shamus/Getty Images

This might be it for many of you, since so many leagues end their season in Week 16, and if that is the case for you and your team(s), then we thank you. Here are the latest PPR flex rankings, combining the best of the running backs, wide receivers and tight ends into one list. As always, there will be injury updates as the week progresses, and if you played for months to get to this point, the least you can do is pay attention later this week. Good luck to all!

1. Christian McCaffrey, RB, Panthers: Not sure there is anything he can do wrong in these final two weeks -- except suffer a major injury -- to remove him from next season's No. 1 pick.
2. Michael Thomas, WR, Saints