At the time, the 37-year-old was at the Sanchez Pizjuan stadium playing in the Champions League group-stage opener against Lens.
Ramos' wife, Pilar Rubio, was also away during the burglary but a source told ESPN the couple's four children and their minders were in the house. No one was hurt during the incident.
Ramos returned to boyhood club Sevilla this summer, 18 years since leaving to join Real Madrid. He won 22 trophies over his 16 years at the club, including the Champions Leagues four times and five LaLiga titles.
In 2021 he retired from international football as Spain's most capped player with 180 senior appearances, and that same year he began his two-year spell at Paris Saint-Germain.