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Buffalo Bills final 53-man roster projection for 2022: CB Tre'Davious White's recovery could alter plans

Bills cornerback Tre'Davious White is recovering from an ACL tear and might not be ready to play Week 1. Mark Konezny/USA TODAY Sports

BUFFALO, N.Y. -- The Buffalo Bills open the 2022 NFL regular season at the Los Angeles Rams on Sept. 8 at SoFi Stadium.

After losing in the playoffs two years in a row to the Kansas City Chiefs at Arrowhead Stadium, the Bills are the favorites to win the Super Bowl this season (+600 per Caesars Sportsbook).

With a roster that is predicted to be among the most talented in the NFL, the number of open roster spots is small. There are a couple of interesting decisions for the Bills to make, including how many tight ends to keep, especially with O.J. Howard's guaranteed money. They also need to navigate the uncertainty surrounding Tre'Davious White's return to the field from a left ACL tear.

In the recent cuts to get the roster down to 80 players, the Bills elected to trade former second-round pick guard Cody Ford to the Arizona Cardinals and placed offensive lineman Ike Boettger on the PUP list to start the season.

The roster will be cut to 53 players by 4 p.m. ET on Tuesday. Here is a projection:


QUARTERBACK (2): Josh Allen, Case Keenum

Nothing has changed here. Keenum was always set to backup Allen, and Matt Barkley should land on the practice squad, similar to how the Bills handled the quarterback room last season with Mitch Trubisky and Davis Webb.