Real Salt Lake will have to soldier on without veteran duo Chad Barrett and David Horst due to long-term injuries.
Striker Barrett and defender Horst, both 31, underwent successful knee surgeries at the Salt Lake Regional Medical Center and will be out of action for four to six months and six to eight weeks respectively.
Horst, 31 had a tibial plateau chondral scope in his right knee while Barrett had to repair a left knee femoral chondral defect and trochlear defect.
"Both surgeries went really well and we anticipate that both players should be able to make full recoveries," said Dr. Andrew Cooper.
Real Salt Lake take on the Vancouver Whitecaps on Saturday with new head coach Mike Petke in charge for the first time.