Find out who is missing through injury, who's in a race against time to prove their fitness and who has been ruled out through suspension for the next round of LaLiga fixtures.
And as you plan your fantasy team for the next gameweek, check out the predicted XIs for all 20 clubs.
Positions: Goalkeeper (GK), Defender (D), Left-back (LB), Right-back (RB), Centre-back (CB), Midfielder (M), Defensive midfield (DM), Central midfield (CM), Left midfield (LM), Right midfield (RM), Attacking midfield (AM), Left winger (LW), Right winger (RW), Forward (F), Left forward (FWL), Right forward (FWR), Striker (ST)
(All predicted XIs and injury news powered by Rotowire and subject to updates.)
Rayo Vallecano v Real Valladolid
Estadio de Vallecas, Madrid
Friday, 8 p.m. GMT / 3 p.m. ET
Latest Rayo Vallecano team news
Expected Lineup:
GK Augusto Batalla
LB Pep Chavarría | CB Florian Lejeune | CB Abdul Mumin | RB Andrei Ratiu
DM Pathé Ciss | DM Unai López
LW Álvaro García | AM Isi Palazón | RW Jorge de Frutos
ST Sergio Camello
Injury/suspension updates:
Raul de Tomás, F, illness, DOUBT
Randy Nteka, F/M, suspension, due back Feb. 17
Latest Real Valladolid team news
Expected Lineup:
GK Karl Hein
LB David Torres | CB Joseph Aidoo | CB Javi Sánchez | RB Luis Pérez
DM Mario Martín
LM Selim Amallah | CM Stanko Juric | CM Tamas Nikitscher | RM Anuar
ST Marcos André
Injury/suspension updates:
Eray Cömert, M/D, hamstring, OUT, estimated return Feb. 23
Florian Grillitsch, M/D, ankle, DOUBT
Raúl Moro, F/M, collarbone, OUT, estimated return Apr. 6
Celta Vigo v Real Betis
Estadio Abanca-Balaídos, Vigo
Saturday, 1 p.m. GMT / 8 a.m. ET
Latest Celta Vigo team news
Expected Lineup:
GK Vicente Guaita
CB Carlos Domínguez | CB Javi Rodríguez | CB Marcos Alonso
LM Mihailo Ristic | CM Fran Beltrán | CM Hugo Sotelo | RM Óscar Mingueza
FWL Williot Swedberg | ST Borja Iglesias | FWR Pablo Durán
Injury/suspension updates:
Iago Aspas, F, calf, DOUBT
Franco Cervi, M, hamstring, OUT, estimated return Mar. 9
Ilaix Moriba, M, suspension, due back Feb. 15
Carl Starfelt, D, suspension, due back Feb. 15
Latest Real Betis team news
Expected Lineup:
GK Adrián
LB Romain Perraud | CB Natan | CB Diego Llorente | RB Angel Ortiz
DM Sergi Altimira | DM Johnny Cardoso
LW Giovani Lo Celso | AM Isco | RW Antony
ST Cédric Bakambu
Injury/suspension updates:
Chimy Ávila, F, knee, DOUBT
Héctor Bellerín, D, foot, DOUBT
William Carvalho, M, achilles, OUT, estimated return May. 4
Aitor Ruibal, D, ankle, DOUBT
Youssouf Sabaly, D, hamstring, OUT, estimated return Feb. 16
Athletic Club v Girona
San Mamés, Bilbao
Saturday, 3:15 p.m. GMT / 10:15 a.m. ET
Latest Athletic Club team news
Expected Lineup:
GK Unai Simón
LB Yuri Berchiche | CB Yeray | CB Dani Vivian | RB Andoni Gorosabel
DM Mikel Jauregizar | DM Beñat Prados
CM Mikel Vesga
LW Nico Williams | RW Iñaki Williams
ST Álex Berenguer
Injury/suspension updates:
Álvaro Djaló, F, ankle, OUT, estimated return Feb. 16
Unai Núñez, D, hamstring, DOUBT
Iñigo Ruiz de Galarreta, M, hamstring, DOUBT
Nico Williams, F/M, hamstring, DOUBT
Latest Girona team news
Expected Lineup:
GK Paulo Gazzaniga
LB Miguel Gutiérrez | CB Ladislav Krejcí | CB David López | RB Arnau Martínez
DM Yangel Herrera | DM Iván Martín
LW Bryan Gil | AM Donny van de Beek | RW Viktor Tsygankov
ST Abel Ruiz
Injury/suspension updates:
Daley Blind, D, undisclosed, DOUBT
Las Palmas v Villarreal
Estadio Gran Canaria, Las Palmas
Saturday, 5:30 p.m. GMT / 12:30 p.m. ET
Latest Las Palmas team news
Expected Lineup:
GK Jasper Cillessen
LB Mika Mármol | CB Scott McKenna | CB Álex Suárez | RB Andy Pelmard
DM Enzo Loiodice | DM Javi Muñoz
LW Alberto Moleiro | AM Stefan Bajcetic | RW Manuel Fuster
ST Fábio Silva
Injury/suspension updates:
Marvin, M/D, undisclosed, OUT, estimated return Feb. 16
José Campaña, M, undisclosed, OUT, estimated return Feb. 23
Adnan Januzaj, F/M, strain, DOUBT
Dário Essugo, M, suspension, due back Feb. 22
Jaime Mata, F/M, suspension, due back Feb. 16
Sandro, F, foot, DOUBT
Kirian Rodríguez, M, illness, OUT, estimated return Jun. 30
Viti, M/D, knee, DOUBT
Latest Villarreal team news
Expected Lineup:
GK Diego Conde
LB Sergi Cardona | CB Juan Foyth | CB Willy Kambwala | RB
LM Álex Baena | CM Santi Comesaña | CM Pape Gueye | RM Yeremy Pino
ST Thierno Barry | ST Ayoze Pérez
Injury/suspension updates:
Ilias Akhomach, F, knee, OUT, estimated return Jul. 1
Alfonso Pedraza, D, ankle, DOUBT
Real Madrid v Atlético Madrid
Santiago Bernabéu, Madrid
Saturday, 8 p.m. GMT / 3 p.m. ET
Latest Real Madrid team news
Expected Lineup:
GK Thibaut Courtois
LB Fran García | CB Raúl Asencio | CB Aurélien Tchouaméni | RB Lucas Vázquez
DM Federico Valverde | DM Dani Ceballos
LW Vinícius Jr. | AM Jude Bellingham | RW Rodrygo
ST Kylian Mbappé
Injury/suspension updates:
David Alaba, D, groin, OUT, estimated return Mar. 2
Eduardo Camavinga, M, hamstring, DOUBT
Dani Carvajal, D, knee, OUT, estimated return Aug. 1
Kylian Mbappé, F, undisclosed, DOUBT
Éder Militão, D, knee, OUT, estimated return Aug. 1
Antonio Rüdiger, D, hamstring, OUT, estimated return Mar. 2
Latest Atlético Madrid team news
Expected Lineup:
GK Jan Oblak
LB César Azpilicueta | CB José María Giménez | CB Clément Lenglet | RB Marcos Llorente
LM Samuel Lino | CM Pablo Barrios | CM Rodrigo De Paul | RM Giuliano Simeone
ST Julián Álvarez | ST Antoine Griezmann
Injury/suspension updates:
Javi Galán, D, ankle, DOUBT
Robin Le Normand, D, suspension, due back Feb. 15
Alavés v Getafe
Mendizorroza, Vitoria-Gasteiz
Sunday, 1 p.m. GMT / 8 a.m. ET
Latest Alavés team news
Expected Lineup:
GK Jesús Owono
LB Manu Sánchez | CB Abdel Abqar | CB Moussa Diarra | RB Nahuel Tenaglia
DM Antonio Blanco | DM Ander Guevara
LW Carlos Martín | AM Jon Guridi | RW Carlos Vicente
ST Enrique García
Injury/suspension updates:
Tomás Conechny, M, head, DOUBT
Joan Jordán, M, undisclosed, DOUBT
Antonio Sivera, G, hand, OUT, estimated return Feb. 16
Latest Getafe team news
Expected Lineup:
GK David Soria
LB Diego Rico | CB Omar Alderete | CB Domingos Duarte | RB Juan Iglesias
LM Coba Da Costa | CM Mauro Arambarri | CM Christantus Uche | CM Djené | RM Carles Pérez
ST Juanmi
Injury/suspension updates:
Luis Milla, M, undisclosed, DOUBT
Allan Nyom, M/D, undisclosed, DOUBT
Valencia v Leganés
Mestalla, Valencia
Sunday, 3:15 p.m. GMT / 10:15 a.m. ET
Latest Valencia team news
Expected Lineup:
GK Giorgi Mamardashvili
LB José Gayà | CB Cristhian Mosquera | CB César Tárrega | RB Max Aarons
DM Enzo Barrenechea | DM Javi Guerra
LW Luis Rioja | AM André Almeida | RW Diego López
ST Hugo Duro
Injury/suspension updates:
Thierry Correia, D, knee, OUT, estimated return Jul. 1
Rafa Mir, F, quadriceps, DOUBT
Latest Leganés team news
Expected Lineup:
GK Marko Dmitrovic
LB Juan Cruz | CB Matija Nastasic | CB Valentin Rosier | CB Jorge | RB Adrià Altimira
CM Yvan Neyou | CM Renato Tapia
AM Óscar Rodríguez
ST Miguel De la Fuente | ST Raba
Injury/suspension updates:
Seydouba Cissé, M, undisclosed, DOUBT
Enric Franquesa, D, knee, OUT, estimated return Sep. 1
Sergio González, D, suspension, due back Feb. 23
Real Sociedad v Espanyol
Reale Arena, San Sebastián
Sunday, 5:30 p.m. GMT / 12:30 p.m. ET
Latest Real Sociedad team news
Expected Lineup:
GK Álex Remiro
LB Aihen Muñoz | CB Nayef Aguerd | CB Igor Zubeldia | RB Jon Aramburu
DM Martín Zubimendi
LM Sergio Gómez | CM Brais Méndez | CM Luka Sucic | RM Takefusa Kubo
ST Mikel Oyarzabal
Injury/suspension updates:
Álvaro Odriozola, D, ribs, DOUBT
Hamari Traoré, D, knee, OUT, estimated return May. 4
Latest Espanyol team news
Expected Lineup:
GK Joan García
LB Brian Oliván | CB Leandro Cabrera | CB Marash Kumbulla | RB Omar El Hilali
DM Álvaro Tejero | DM Pol Lozano
LW Javier Puado | AM Alex Král | RW Jofre Carreras
ST Roberto Fernández
Injury/suspension updates:
Urko Gonzalez de Zarate, M, not injury related, OUT, estimated return Feb. 16
José Gragera, M, illness, DOUBT
Brian Oliván, D, undisclosed, DOUBT
Carlos Romero, D, suspension, due back Feb. 16
Sevilla v Barcelona
Ramón Sánchez-Pizjuán, Sevilla
Sunday, 8 p.m. GMT / 3 p.m. ET
Latest Sevilla team news
Expected Lineup:
GK Ørjan Nyland
LB Enrique Salas | CB Loïc Badé | CB Nemanja Gudelj | RB Juanlu Sanchez
CM Albert Sambi Lokonga | CM Saúl Ñíguez | CM Djibril Sow
FWL Ruben Vargas | ST Isaac Romero | FWR Dodi Lukebakio
Injury/suspension updates:
José Ángel Carmona, M/D, suspension, due back Feb. 16
Tanguy Nianzou, D, thigh, OUT, estimated return Apr. 13
Latest Barcelona team news
Expected Lineup:
GK Wojciech Szczesny
LB Alejandro Balde | CB Ronald Araújo | CB Pau Cubarsí | RB Jules Koundé
CM Marc Casadó | CM Pedri | CM Gavi
FWL Raphinha | ST Robert Lewandowski | FWR Lamine Yamal
Injury/suspension updates:
Marc Bernal, M/D, knee, OUT, estimated return Sep. 1
Andreas Christensen, D, calf, OUT, estimated return Feb. 17
Gavi, M, head, DOUBT
Marc-André ter Stegen, G, knee, OUT, estimated return Apr. 6
Mallorca v Osasuna
Estadi Mallorca Son Moix, Mallorca
Monday, 8 p.m. GMT / 3 p.m. ET
Latest Mallorca team news
Expected Lineup:
GK Dominik Greif
LB Johan Mojica | CB Antonio Raíllo | CB Martin Valjent | RB Pablo Maffeo
LM Sergi Darder | CM Samú Costa | CM Omar Mascarell | RM Dani Rodríguez
ST Cyle Larin | ST Vedat Muriqi
Injury/suspension updates:
Pablo Maffeo, D, undisclosed, DOUBT
Manu Morlanes, M, knee, OUT, estimated return Sep. 1
Antonio Sánchez, M, hamstring, DOUBT
Latest Osasuna team news
Expected Lineup:
GK Sergio Herrera
LB Juan Cruz | CB Flavien-Enzo Boyomo | CB Alejandro Catena | RB Jesús Areso
CM Jon Moncayola | CM Aimar Oroz | CM Lucas Torró
FWL Enrique Barja | ST Ante Budimir | FWR Rubén García
Injury/suspension updates:
Enrique Barja, F/M, undisclosed, DOUBT