AC Milan will face CSU Craiova while Everton will take on either Ruzomberok or Brann in their Europa League third qualifying round ties.
Seven-time European champions Milan, playing the Europa League for the first time, return to continental competition for the first time since the 2013-14 season and will be hopeful of progress against Romanian side Craiova after a positive summer in the transfer market.
Everton, meanwhile, finished seventh last season in the Premier League and were England's top seeds in Friday's draw in Nyon, with Manchester United having secured a place in the Champions League after winning the Europa League final against Ajax last season.
Norwegian side Brann currently hold a slender 1-0 lead from the first leg of their second qualifying round tie against Ruzomberok, which was played on Thursday night in Slovakia. The second leg will be on July 20.
Dutch team PSV Eindhoven will take on the winner of Croatian outfit Osijek or Swiss club Luzern while Turkish giants Fenerbahce meet Austrians Sturm Graz or Mladost Podgorica of Montenegro.
The #UEL draw has spoken - our next opponents in the third qualifying round of the @EuropaLeague are @CSUCOfficial pic.twitter.com/BlT9PZDEuW
- AC Milan (@acmilan) July 14, 2017
Marseille tackle Oostende of Belgium, while Athletic Bilbao play Dinamo Bucharest.
Scottish Premiership side Aberdeen will meet either Apollon Limassol of Cyprus or Moldovan outfit Zaria Balti, if they can get past NK Siroki Brijeg. The Bosnians secured a 1-1 draw in the first leg of the second-qualifying round tie with the Dons at Pittodrie on Thursday.
Friday's draw saw 29 fixtures decided, which were split into five groups, with the first legs set to be played on July 27 and the second on Aug. 3.
The winners will then advance to the Europa League playoff round, which will also include the 15 losers from the Champions League third qualifying round.
The draw for the Europa League group stages will be made on Aug. 25, with 16 teams having gained automatic entry -- including FA Cup winners Arsenal, who finished fifth in the Premier League to miss out on the Champions League for the first time in 20 years.