Lions RB Kerryon Johnson (knee), CB Darius Slay (hamstring) ruled out

DETROIT -- The Detroit Lions lost two of their top players to injury during the first half of Sunday's game against Minnesota.

Running back Kerryon Johnson (right knee) and Pro Bowl cornerback Darius Slay (hamstring) both left the game in the second quarter and did not return.

Slay, who has been battling a hamstring injury since Week 3 against Philadelphia that caused him to miss the following week's game against Kansas City, left the game in the second quarter with a similar injury. He tried to loosen the hamstring up on the stationary bicycle, but he was ruled out before the second half started.

He had given up two big plays -- a touchdown to Adam Thielen and a long pass to Stefon Diggs -- before leaving the game and having doctors look at his hamstring. Justin Coleman replaced Slay in base defensive sets at corner for the Lions and Mike Ford entered in nickel situations.

Johnson left in the second quarter with a right knee injury and then had a brace on the knee. He also tried to get loose on the bike, but did not return and was replaced by rookie Ty Johnson. Kerryon Johnson had five carries for 23 yards before his departure.

Kerryon Johnson missed the second half of the 2018 season with a left knee injury.