The story of this NFL season from a gambling perspective has been how well road teams had performed. In Weeks 1-8, road teams were covering at a 62% clip, and for the first time since the merger, road teams actually had a winning record outright.
That all changed in Week 9. Home teams were 12-2 against the spread (ATS), matching the best week in the Super Bowl era.
As for this weekend, here are some of the top trends to watch in Week 10.
Arizona Cardinals at Tampa Bay Buccaneers (-5, 52), 1 p.m. ET
• Buccaneers quarterback Jameis Winston is 4-11 ATS and 7-8 straight up (SU) as a favorite in his career. He is 1-7 ATS and 3-5 SU as a favorite of at least three points.
• Arizona is 6-2 ATS as an underdog this season (3-1 on the road).
• Since 2013, the Cardinals are 19-9 ATS on the road against teams below .500
Atlanta Falcons at New Orleans Saints (-13.5, 51.5), 1 p.m. ET
• Atlanta is 7-17 ATS over the past two seasons, the worst mark in the NFL (2-6 ATS this season). However, it is 3-3 ATS in division games in that span.
• In division games in which both teams are coming off a bye, the favorite is 10-4-1 ATS under the current divisional format (since 2002).
• New Orleans has covered six consecutive games, the longest active streak in the NFL.
• Over the past five seasons, Saints quarterback Drew Brees is 15-7 ATS in division games.
Baltimore Ravens (-10.5, 44.5) at Cincinnati Bengals, 1 p.m. ET
• Baltimore is 33-0 all time as a double-digit favorite, the only active franchise to never lose such a game. However, over the past 10 seasons, the Ravens are just 3-10 ATS in those games (0-2 this season).
• Home underdogs of at least seven points are 24-10 ATS all time coming off a bye.
• Cincinnati has covered each of the past four meetings, including twice in Lamar Jackson starts.
• The Bengals have not been double-digit home underdogs since 2000. In the Super Bowl era, Cincinnati is 12-3 ATS as a double-digit home underdog.
Buffalo Bills at Cleveland Browns (-3, 40), 1 p.m. ET
• This is the seventh time in the past 25 seasons a team with a winning percentage of .250 or lower is favored over a team with a winning percentage of .750 or better in Week 6 or later. The favorite is 6-0 ATS in the previous six games. It's just the third time in the Super Bowl era it's happened in Week 10 or later (2-0 ATS).
• Browns quarterback Baker Mayfield is 1-4 ATS and 2-3 SU as a favorite in his career.
• When the total is 41 or below, the home team is 14-6 ATS this season. Over the past five seasons, home teams are 107-85-6 ATS in those games.
Detroit Lions at Chicago Bears (-2.5, 42), 1 p.m. ET
• Chicago and Detroit enter their Week 10 matchup on extended losing streaks against the spread. Detroit has failed to cover three straight and Chicago has failed to cover four straight, all straight-up losses. In the past 20 years, the team with the better season ATS record is 23-4 in matchups in which both teams enter the game with at least three-game losing streaks ATS. So far this season, the Lions are 4-4 ATS and the Bears are 2-6.
• The under is 10-3 in Chicago's last 13 games.
• Lions coach Matt Patricia is 5-1 ATS on the road against teams that entered with losing records, though the only non-cover came last weekend at Oakland.
• Chicago has failed to cover in four consecutive games, its longest single-season streak since 2013.
Kansas City Chiefs (-6, 48) at Tennessee Titans, 1 p.m. ET
• Coach Andy Reid is 1-7 SU and 2-6 ATS against Tennessee in his career. Each of the past three meetings, his team lost outright as a favorite (all since 2014).
• Chiefs quarterback Patrick Mahomes is 9-3-1 ATS on the road in his career, and the over is 10-3 in those games.
• The Titans are 5-1 ATS and 4-2 SU as underdogs of at least four points in the Mike Vrabel era.
New York Giants (-2.5, 44.5) at New York Jets, 1 p.m. ET
• In the past five seasons, there have been 15 matchups in Week 6 or later between two teams with winning percentages of .250 or lower. All 15 times, the underdog covered, going 14-1 SU.
• While this game is in their home stadium, the Giants will technically be the road team. They are 9-3 ATS in road games under Pat Shurmur (1-0 ATS as a road favorite).
• The Jets are 7-16-1 ATS over the past two seasons, the second-worst mark in the NFL (2-6 ATS this season).
Miami Dolphins at Indianapolis Colts (-11, 44), 4:05 p.m. ET
• Miami has covered four consecutive games after starting the season 0-4 ATS. It's the second-longest active cover streak in the NFL, behind only New Orleans (six straight).
• Colts coach Frank Reich is 1-4 ATS as a favorite of more than a field goal. This is the first time he is favored by double digits.
• Colts quarterback Brian Hoyer has never been more than a 6.5-point favorite in his career. In 10 starts when Hoyer has been the favorite, the under is 9-1.
• Over the past 10 seasons, teams 1-5 or worse coming off their first victories of the season are 7-10 ATS.
Carolina Panthers at Green Bay Packers (-6, 47), 4:25 p.m. ET
• Carolina's Kyle Allen is 6-1 ATS and SU as a starter (3-1 as an underdog). In the past 10 seasons, the only quarterbacks to start their careers 7-1 or better ATS are Patrick Mahomes, Dak Prescott, Brian Hoyer and Andy Dalton.
• Green Bay is 4-1 ATS this season against teams that entered with winning records.
Los Angeles Rams (-3.5, 44) at Pittsburgh Steelers, 4:25 p.m. ET
• Rams coach Sean McVay is 7-3 ATS and 8-2 SU when having at least nine days to prepare.
• Since 2002 (current divisional alignment), road favorites coming off a bye are 65-35-1 ATS.
• McVay is 10-0 SU and 7-2-1 ATS against AFC teams in regular-season games.
• The Rams are 3-0 ATS this season as a road favorite.
• Steelers coach Mike Tomlin is 9-4-1 ATS and 6-7 SU as a home underdog (3-2-1 ATS, 2-4 SU in games started by quarterbacks other than Ben Roethlisberger).
Minnesota Vikings at Dallas Cowboys (-3, 48), 8:20 p.m. ET
• Minnesota is 1-9-1 ATS in prime-time games since 2009.
• The Vikings are 2-9-1 both ATS and straight up in Kirk Cousins' starts against teams that entered with winning records (0-7-1 on the road).
• Vikings coach Mike Zimmer is 23-9-1 ATS after a loss.
• Cousins is 1-7 SU and 1-6-1 ATS in prime-time games on the road in his career.
• Cowboys quarterback Dak Prescott is 4-0 (3-1 ATS) in his career against Cousins. All four games went over the total.
• Dallas is 1-6 ATS after a Monday game in the Jason Garrett era.
• The under is 13-4 in Sunday night and Monday night games this season.
• When the home team has been favored in Sunday and Monday prime-time games this season, all eight games have gone under the total.
Seattle Seahawks at San Francisco 49ers (-6, 46.5), Monday, 8:15 p.m. ET
• Seattle is 8-2 ATS in its past 10 road games dating back to last season. During that span, it's 6-0 ATS as a road underdog. This season, the Seahawks are 4-0 SU and 3-1 ATS on the road.
• In the past 35 seasons, teams 4-0 or better are 12-2-1 ATS in divisional games on Monday night.
• Seahawks quarterback Russell Wilson is 12-3 ATS and SU in his career against San Francisco. However, the 49ers are 2-3 ATS in his past five games.
• Home teams have failed to cover four consecutive games on Monday Night Football. Overall, home teams are 3-7 ATS on Mondays this season. Seven of the 10 games went under.