Whom should you start? Whom should you sit? To help you set your fantasy football lineups and avoid starting an offensive player who won't be in the lineup, we'll post fantasy-relevant updates and analysis here as NFL teams release their official inactives lists. Any rankings cited in this column come from our ESPN Fantasy staff ranks.
Official Sunday inactives should begin coming in approximately 90 minutes before the scheduled kickoff times: around 11:30 a.m. ET for the early games and 2:30 p.m. ET for the late-afternoon games.
Refresh often for the latest information.
4 p.m. ET games
Matt Prater, K, ARI: Knee -- Inactive
Impact: Chad Ryland is the last-minute replacement for the Cardinals.
Trey McBride, TE, ARI: Ribs -- Active
Impact: He will try to play but was a Saturday add to the injury report. It's probably best to err on the side of caution and start someone else.
Tyler Badie, RB, DEN: Back -- OUT/IR
Impact: Javonte Williams and Jaleel McLaughlin share the workload in this thus-far-unimpressive backfield.
Greg Dulcich, TE, DEN: Team decision -- Inactive
Impact: Dulcich has disappointed, with only 28 yards this season. Lucas Krull and Adam Trautman will get the TE targets in this one.
Luke Musgrave, TE, GB: Ankle -- Active
Impact: He is apparently good enough to go and may eat into Tucker Kraft's target count.
Romeo Doubs, WR, GB: Suspended by team for one game
Impact: Jayden Reed and Dontayvion Wicks will start after Doubs missed a few practices this week and the team felt discipline was required.
Christian Watson, WR, GB: Ankle -- Inactive
Impact: Perhaps Malik Heath or Bo Melton could surprise.
Cooper Kupp, WR, LAR: Ankle -- OUT
Impact: With the Rams getting their bye in Week 6, expect a Week 7 return for Kupp.
Zamir White, RB, LV: Groin -- OUT
Impact: Alexander Mattison: There are a million things he hasn't done, but just you wait.
Michael Mayer, TE, LV: Personal -- OUT
Impact: Just covering the bases with this news. Brock Bowers has a firm grasp on the TE job here.
Davante Adams, WR, LV: Hamstring -- OUT
Impact: Yes, trade talks are swirling, but the team says the injury is real. In any event, Tre Tucker and Jakobi Meyers once again get starting nods.
Tyreik McAllister, WR, LV: Shoulder -- Inactive
Impact: DJ Turner is the only other healthy WR option in Las Vegas.
Devin Singletary, RB, NYG: Groin -- Inactive
Impact: It's a huge downgrade to a timeshare between Tyrone Tracy Jr. and Eric Gray.
Malik Nabers, WR, NYG: Concussion -- OUT
Impact: Wan'Dale Robinson leads an otherwise nondescript group of WR options.
George Kittle, TE, SF: Ribs -- Active
Impact: Eric Saubert would step in should Kittle suffer a setback during the contest.
Sunday night game
Brandin Cooks, WR, DAL: Knee -- OUT/IR
Impact: Jalen Tolbert and KaVontae Turpin could both end up being beneficiaries of Cooks' absence.
Russell Wilson, QB, PIT: Calf -- Questionable
Impact: You know the drill. Justin Fields will start. Wilson will be the emergency QB No. 3.
Cordarrelle Patterson, RB, PIT: Ankle -- OUT
Impact: Najee Harris is free and clear to get nearly all of the RB touches.
Jaylen Warren, RB, PIT: Knee -- OUT
Impact: If you're extremely desperate, Aaron Shampklin might see some snaps.
9:30 a.m. ET game (London)
T.J. Hockenson, TE, MIN: Knee -- OUT
Impact: His return window is now open. Consider Week 7 as a likely target date.
1 p.m. ET games
Rasheen Ali, RB, BAL: Neck -- Not activated
Impact: However, the rookie practiced this week and looks close to a return from IR. Once he does, he will provide extra backup for Derrick Henry. Chris Collier was called up from the practice squad.
Khalil Shakir, WR, BUF: Ankle -- OUT
Impact: Curtis Samuel is one of the receivers to get a bump in value.
Ian Thomas, TE, CAR: Calf -- OUT
Impact: He was "designated for return" this week, so he now has three weeks to practice with the team in the hopes of getting back into action.
Nick Chubb, RB, CLE: Knee -- OUT
Impact: Perhaps next week will be the week he returns to the lineup following last year's torn ACL. Jerome Ford is still the No. 1 RB for now.
Nyheim Hines, RB, CLE: Knee -- OUT
Impact: Chubb's fellow ACL-recoveree also saw his window to return open this week.
Pierre Strong Jr., RB, CLE: Hamstring -- Active
Impact: Even so, D'Onta Foreman may still continue to be involved in the Browns' backfield.
David Njoku, TE, CLE: Ankle -- Active
Impact: Until we see him on the field for a full 60 minutes, it's hard to trust him for fantasy.
Joe Mixon, RB, HOU: Ankle -- OUT
Impact: No practice all week once again puts the RB spotlight on Cam Akers.
Dameon Pierce, RB, HOU: Hamstring -- Inactive
Impact: Dare Ogunbowale is making the most of his opportunity to see more action with all these RB injuries.
Robert Woods, WR, HOU: Foot -- Active
Impact: Meanwhile, WR Tank Dell (chest) was able to practice all three days this week and should start.
Anthony Richardson, QB, IND: Oblique -- Inactive
Impact: The Colts downgraded him Saturday. Veteran Joe Flacco stands at the ready.
Jonathan Taylor, RB, IND: Ankle -- OUT
Impact: It will be a committee featuring Trey Sermon and Tyler Goodson in the Colts' backfield.
Evan Engram, TE, JAX: Hamstring -- Inactive
Impact: Are you surprised? Brenton Strange will start yet again this week.
Skylar Thompson, QB, MIA: Ribs -- Inactive
Impact: Tyler Huntley will start, with Tim Boyle (waived and then re-signed this week) backing him up.
Jeff Wilson Jr., RB, MIA: Team decision -- Inactive
Impact: He's not needed, with both Raheem Mostert and De'Von Achane ready to roll.
Odell Beckham Jr., WR, MIA: Knee -- Active
Impact: Beckham started this past week still on the PUP list. His Saturday activation means he should see some targets today.
K.J. Osborn, WR, NE: Shoulder -- Inactive
Impact: Expect DeMario Douglas and Ja'Lynn Polk to get the bulk of WR targets.
Kendrick Bourne, WR, NE: Knee -- Active
Impact: Bourne was activated from the PUP list Saturday, which indicates he's ready to play.
Brian Robinson Jr., RB, WAS: Knee -- Active
Impact: He will play, as will Austin Ekeler, who was finally cleared from the league's concussion protocol.
Noah Brown, WR, WAS: Groin -- OUT
Impact: Luke McCaffrey and Olamide Zaccheaus get upticks in value. Jamison Crowder (calf) was placed on IR.