Find out who is missing through injury, who's in a race against time to prove their fitness and who has been ruled out through suspension for the next round of LaLiga fixtures.
And as you plan your fantasy team for the next gameweek, check out the predicted XIs for all 20 clubs.
Positions: Goalkeeper (GK), Defender (D), Left-back (LB), Right-back (RB), Centre-back (CB), Midfielder (M), Defensive midfield (DM), Central midfield (CM), Left midfield (LM), Right midfield (RM), Attacking midfield (AM), Left winger (LW), Right winger (RW), Forward (F), Left forward (FWL), Right forward (FWR), Striker (ST)
(All predicted XIs and injury news powered by Rotowire and subject to updates.)
Getafe v Real Valladolid
Estadio Coliseum, Getafe
Friday, 3 p.m. ET / 8 p.m. UK
Latest Getafe team news
Expected Lineup:
GK David Soria
LB Diego Rico | CB Omar Alderete | CB Djené | RB Juan Iglesias
DM Mauro Arambarri | DM Luis Milla
LW Álex Sola | AM Christantus Uche | RW Carles Pérez
ST Bertug Yildirim
Injury/suspension updates:
Djené, M/D, hamstring, DOUBT
Borja Mayoral, F, strain, OUT, estimated return Dec. 1
Latest Real Valladolid team news
Expected Lineup:
GK Karl Hein
LB Lucas Rosa | CB Juma Bah | CB Javi Sánchez | CB David Torres | RB Luis Pérez
LM Anuar | CM Stanko Juric | CM Kike Perez | RM Raúl Moro
ST Mamadou Diallo
Injury/suspension updates:
César De la Hoz, M, back, DOUBT
Kenedy, F/M, undisclosed, DOUBT
Valencia v Real Betis
Mestalla, Valencia
Saturday, 8 a.m. ET / 1 p.m. UK
Latest Valencia team news
Expected Lineup:
GK Giorgi Mamardashvili
LB José Gayà | CB Maximiliano Caufriez | CB Cristhian Mosquera | CB Cesar Tarrega | RB Dimitri Foulquier
LM Luis Rioja | CM Enzo Barrenechea | CM Javier Guerra | RM Diego Lopez
ST Hugo Duro
Injury/suspension updates:
Thierry Correia, D, knee, OUT, estimated return Jul. 1
Mouctar Diakhaby, D, knee, OUT, estimated return Dec. 7
Hugo Duro, F/M, groin, DOUBT
Pepelu, M, suspension, due back Nov. 29
Rafa Mir, F, personal, DOUBT
Jesus Vazquez Alcalde, D, thigh, DOUBT
Latest Real Betis team news
Expected Lineup:
GK Rui Silva
LB Romain Perraud | CB Natan | CB Diego Llorente | RB Youssouf Sabaly
DM Sergi Altimira | DM Johnny Cardoso
LW Abde Ezzalzouli | AM Giovani Lo Celso | RW Pablo Fornals
ST Vitor Roque
Injury/suspension updates:
Isco, F/M, leg, OUT, estimated return Dec. 1
William Carvalho, M, achilles, OUT, estimated return May. 4
Johnny Cardoso, M, thigh, DOUBT
Marc Roca, M, ankle, OUT, estimated return Dec. 15
Aitor Ruibal, D, thigh, DOUBT
Atlético Madrid v Alavés
Riyadh Air Metropolitano, Madrid
Saturday, 10:15 a.m. ET / 3:15 p.m. UK
Latest Atlético Madrid team news
Expected Lineup:
GK Jan Oblak
CB José María Giménez | CB Clément Lenglet | CB Reinildo Mandava
LM Rodrigo Riquelme | CM Pablo Barrios | CM Koke | RM Samuel Lino
AM Antoine Griezmann | AM Giuliano Simeone
ST Julián Álvarez
Injury/suspension updates:
César Azpilicueta, D, leg, DOUBT
Robin Le Normand, D, concussion, DOUBT
Thomas Lemar, M, undisclosed, DOUBT
Marcos Llorente, M/D, thigh, DOUBT
Nahuel Molina, M/D, thigh, OUT, estimated return Nov. 30
Latest Alavés team news
Expected Lineup:
GK Antonio Sivera
LB Manu Sánchez | CB Abdel Abqar | CB Aleksander Sedlar | RB Nahuel Tenaglia
DM Antonio Blanco | DM Ander Guevara
LW Abde Rebbach | AM Jon Guridi | RW Carlos Vicente
ST Enrique García
Injury/suspension updates:
Hugo Novoa, M, abdomen, DOUBT
Carlos Benavídez, M, undisclosed, DOUBT
Girona v Espanyol
Municipal de Montilivi, Girona
Saturday, 12:30 p.m. ET / 5:30 p.m. UK
Latest Girona team news
Expected Lineup:
GK Paulo Gazzaniga
CB Daley Blind | CB David López | CB Juanpe
LM Miguel Gutiérrez | CM Yangel Herrera | CM Oriol Romeu | CM Donny van de Beek | RM Arnau Martínez
ST Bojan Miovski | ST Bryan Gil
Injury/suspension updates:
Ricard Artero, M, ankle, DOUBT
Yáser Asprilla, M, ankle, DOUBT
Arnaut Danjuma, F/M, hamstring, OUT, estimated return Dec. 8
Alejandro Francés, D, hamstring, DOUBT
Jastin García, F/M, shoulder, OUT, estimated return Dec. 22
Yangel Herrera, M, undisclosed, DOUBT
Pau López, G, hand, DOUBT
Portu, F/M, ankle, DOUBT
Iván Martín, M, groin, DOUBT
Gabriel Misehouy, M, hamstring, OUT, estimated return Dec. 10
Abel Ruiz, F, groin, DOUBT
Jhon Solis, M, thigh, DOUBT
Viktor Tsygankov, M, hamstring, DOUBT
Latest Espanyol team news
Expected Lineup:
GK Joan García
CB Leandro Cabrera | CB Omar El Hilali | CB Marash Kumbulla
LM Carlos Romero | CM Alvaro Aguado | CM Alex Král | RM Álvaro Tejero
AM Jofre Carreras | AM Javi Puado
ST Alejo Veliz
Injury/suspension updates:
Fernando Calero, D, achilles, DOUBT
Edu Exposito, M, knee, OUT, estimated return Dec. 8
José Gragera, M, illness, DOUBT
Marash Kumbulla, D, undisclosed, DOUBT
Pol Lozano, M, undisclosed, DOUBT
Las Palmas v Mallorca
Estadio Gran Canaria, Las Palmas
Saturday, 12:30 p.m. ET / 5:30 p.m. UK
Latest Las Palmas team news
Expected Lineup:
GK Jasper Cillessen
LB Álex Muñoz | CB Scott McKenna | CB Álex Suárez | RB Viti
CM Dário Essugo | CM Javier Munoz | CM Kirian Rodríguez
FWL Alberto Moleiro | ST Fábio Silva | FWR Sandro
Injury/suspension updates:
Marvin, M/D, hamstring, DOUBT
Enzo Loiodice, M, undisclosed, DOUBT
Latest Mallorca team news
Expected Lineup:
GK Dominik Greif
LB Johan Mojica | CB Antonio Raíllo | CB Martin Valjent | RB Pablo Maffeo
LM Sergi Darder | CM Samú Costa | CM Manu Morlanes | RM Robert Navarro
ST Cyle Larin | ST Vedat Muriqi
Injury/suspension updates:
Takuma Asano, F, strain, DOUBT
Valery Fernández, M, undisclosed, DOUBT
Javi Llabrés, F/M, thigh, DOUBT
Celta Vigo v Barcelona
Estadio Abanca-Balaídos, Vigo
Sunday, 3 p.m. ET / 8 p.m. UK
Latest Celta Vigo team news
Expected Lineup:
GK Vicente Guaita
CB Javier Rodriguez | CB Carl Starfelt | CB Marcos Alonso
LM Mihailo Ristic | CM Fran Beltrán | CM Hugo Sotelo | RM Óscar Mingueza
AM Iago Aspas | AM Williot Swedberg
ST Borja Iglesias
Injury/suspension updates:
Sergio Carreira, D, ankle, DOUBT
Luca de la Torre, M, ankle, DOUBT
Jailson, M, groin, DOUBT
Latest Barcelona team news
Expected Lineup:
GK Iñaki Peña
LB Alejandro Balde | CB Iñigo Martínez | CB Pau Cubarsí | RB Jules Koundé
DM Marc Casadó | DM Pedri
LW Raphinha | AM Dani Olmo | RW Fermín López
ST Robert Lewandowski
Injury/suspension updates:
Ronald Araújo, D, hamstring, DOUBT
Marc Bernal, M/D, knee, OUT, estimated return Sep. 1
Andreas Christensen, D, achilles, OUT, estimated return Nov. 26
Frenkie de Jong, M, undisclosed, DOUBT
Ansu Fati, F, hamstring, OUT, estimated return Dec. 11
Hector Fort, D, back, DOUBT
Eric García, D, groin, DOUBT
Robert Lewandowski, F, back, DOUBT
Marc-André ter Stegen, G, knee, OUT, estimated return Apr. 6
Ferran Torres, F, hamstring, OUT, estimated return Dec. 15
Lamine Yamal, F, ankle, OUT
Osasuna v Villarreal
El Sadar, Pamplona
Sunday, 8 a.m. ET / 1 p.m. UK
Latest Osasuna team news
Expected Lineup:
GK Sergio Herrera
LB Juan Cruz | CB Flavien-Enzo Boyomo | CB Alejandro Catena | RB Jesús Areso
CM Jon Moncayola | CM Aimar Oroz | CM Lucas Torró
FWL Bryan Zaragoza | ST Ante Budimir | FWR Rubén Peña
Injury/suspension updates:
Juan Cruz, D, leg, DOUBT
Iker Benito, F, groin, OUT, estimated return Dec. 2
Latest Villarreal team news
Expected Lineup:
GK Diego Conde
LB Sergi Cardona | CB Raúl Albiol | CB Logan Costa | RB Pau Navarro
LM Álex Baena | CM Pape Gueye | CM Dani Parejo | RM Yeremy Pino
ST Jorge Pascual | ST Gerard Moreno
Injury/suspension updates:
Ilias Akhomach, F, knee, OUT, estimated return Jul. 1
Álex Baena, M, ankle, DOUBT
Eric Bailly, D, shoulder, DOUBT
Juan Foyth, D, knee, DOUBT
Gerard Moreno, F, hip, DOUBT
Alfonso Pedraza, D, ankle, OUT, estimated return Dec. 15
Nicolas Pépé, F/M, thigh, OUT, estimated return Dec. 1
Ayoze Pérez, F/M, thigh, OUT, estimated return Dec. 1
Sevilla v Rayo Vallecano
Ramón Sánchez-Pizjuán, Sevilla
Sunday, 10:15 a.m. ET / 3:15 p.m. UK
Latest Sevilla team news
Expected Lineup:
GK Álvaro Fernández
LB Adrià Pedrosa | CB Loïc Badé | CB Enrique Salas | RB José Ángel Carmona
CM Albert Sambi Lokonga | CM Djibril Sow | CM Nemanja Gudelj
FWL Kelechi Iheanacho | ST Isaac Romero | FWR Dodi Lukebakio
Injury/suspension updates:
Lucien Agoumé, M, suspension, due back Dec. 2
Loïc Badé, D, thigh, DOUBT
Chidera Ejuke, F, hamstring, OUT, estimated return Dec. 1
Suso, F/M, groin, DOUBT
Stanis Idumbo, F/M, groin, DOUBT
Tanguy Nianzou, D, thigh, OUT, estimated return Dec. 22
Saúl Ñíguez, M, thigh, DOUBT
Ørjan Nyland, G, knee, OUT, estimated return Dec. 1
Latest Rayo Vallecano team news
Expected Lineup:
GK Augusto Batalla
LB Pep Chavarría | CB Florian Lejeune | CB Abdul Mumin | RB Andrei Ratiu
CM Unai López | CM Óscar Valentín | CM Isi Palazón
FWL Álvaro García | ST Sergio Camello | FWR Jorge de Frutos
Injury/suspension updates:
Alfonso Espino, D, fracture, DOUBT
Leganés v Real Madrid
Butarque, Leganés, Madrid
Sunday, 12:30 p.m. ET / 5:30 p.m. UK
Latest Leganés team news
Expected Lineup:
GK Marko Dmitrovic
LB Javi Hernández | CB Sergio González | CB Matija Nastasic | RB Adrià Altimira
DM Seydouba Cissé | DM Yvan Neyou
LW Munir El Haddadi | AM Darko Brasanac | RW Juan Cruz
ST Miguel De la Fuente
Injury/suspension updates:
Enric Franquesa, D, knee, OUT, estimated return Sep. 1
Diego Garcia, F, strain, DOUBT
Raba, F, hamstring, DOUBT
Latest Real Madrid team news
Expected Lineup:
GK Thibaut Courtois
LB Fran GarcíaCB Antonio Rüdiger | RB Federico Valverde
CM Jude Bellingham | CM Eduardo Camavinga | CM Luka Modric
FWL Vinícius Jr. | ST Kylian Mbappé | FWR Brahim Díaz
Injury/suspension updates:
David Alaba, D, knee, DOUBT
Dani Carvajal, D, knee, OUT, estimated return Aug. 1
Thibaut Courtois, G, groin, DOUBT
Éder Militão, D, knee, OUT, estimated return Aug. 1
Rodrygo, F/M, undisclosed, DOUBT
Aurélien Tchouaméni, M, ankle, DOUBT
Lucas Vázquez, M/D, groin, DOUBT
Athletic Club v Real Sociedad
San Mamés, Bilbao
Sunday, 3 p.m. ET / 8 p.m. UK
Latest Athletic Club team news
Expected Lineup:
GK Julen Agirrezabala
LB Yuri Berchiche | CB Aitor Paredes | CB Dani Vivian | RB Óscar de Marcos
DM Mikel Jauregizar | DM Iñigo Ruiz de Galarreta
LW Nico Williams | AM Oihan Sancet | RW Iñaki Williams
ST Gorka Guruzeta
Injury/suspension updates:
Álex Berenguer, F/M, abdomen, DOUBT
Unai Simón, G, wrist, OUT, estimated return Dec. 15
Latest Real Sociedad team news
Expected Lineup:
GK Álex Remiro
LB Aihen Muñoz | CB Nayef Aguerd | CB Igor Zubeldia | RB Jon Aramburu
CM Brais Méndez | CM Luka Sucic | CM Martín Zubimendi
FWL Sheraldo Becker | ST Mikel Oyarzabal | FWR Takefusa Kubo
Injury/suspension updates:
Pablo Marín, M, undisclosed, DOUBT
Umar Sadiq, F, strain, OUT, estimated return Nov. 28
Hamari Traoré, D, knee, OUT, estimated return May. 4
Beñat Turrientes, M, calf, DOUBT
Arsen Zakharyan, M, ankle, DOUBT
Martín Zubimendi, M, hip, DOUBT