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Experts predict NFL Week 12 upset picks, fantasy football sleepers and flops, plus the AFC South winner

Week 12 of the 2020 NFL schedule features three games on Thanksgiving Day, capped by a showdown between AFC North rivals Baltimore (6-4) and Pittsburgh (10-0) at Heinz Field.

The holiday weekend continues on Sunday with several intriguing matchups, including the interconference showdown between Kansas City (9-1) and Tampa Bay (7-4) at Raymond James Stadium and Round 2 between Tennessee (7-3) and Indianapolis (7-3) for AFC South supremacy, this time at Lucas Oil Stadium.

We asked our experts to pick between the Titans and Colts, as well as the biggest potential upsets, fantasy football flops and sleepers, and what football fans should be most thankful for in this strange year.

Quick links:
Schedule | Depth charts | PickCenter

What's your top upset pick for Week 12?

Matt Bowen, NFL analyst: Panthers (+4) over Vikings. The Minnesota run game with Dalvin Cook makes this pick a little shaky, but I'm going with the scheme of Panthers offensive coordinator Joe Brady here. Look for Brady to set up quarterback Teddy Bridgewater with high-percentage throws versus the Vikings' split-safety coverages.

Jason Reid, The Undefeated senior NFL writer: Washington (+3.0) over the Cowboys. Don't be surprised if Washington's talented defensive line has its best outing of the season because, well, the Cowboys' offensive front simply isn't what it once was. A big performance from rookie defensive end Chase Young, the second overall pick, could help Washington earn its fourth victory and move into first place in the disappointing -- to say the least -- NFC East.