Win the Weekend: Come out on top with our fantasy and betting tips

Stephania Bell's injury update

• San Francisco 49ers RB Christian McCaffrey suffered an oblique/rib injury in last Sunday's game and briefly left in the third quarter, returned for one 6-yard run late in the same quarter, then exited again and did not return. Before he went to the locker room (after his second exit) McCaffrey could be seen performing stretches on the sideline. It was unclear when exactly he was injured, and the 49ers were uncertain initially whether it was an oblique muscle injury, a rib injury or both. After McCaffrey underwent an MRI on Monday, the 49ers sounded more optimistic about his potential to return for Monday night's game, calling his status day-to-day. Expect the Niners -- and McCaffrey -- to allow him up to game time to make the decision on his availability. McCaffrey did not practice Thursday.

• Get all the latest injury news here.

Matt Bowen's matchups to exploit

• Pittsburgh Steelers WR George Pickens in 3x1 sets vs. the Los Angeles Rams defense: Pickens logged four explosive-play receptions (reception of 20 or more yards) in the Steelers' Week 5 win over the Baltimore Ravens. And I see opportunities for the Steelers to isolate Pickens versus the Rams as the boundary X receiver. Whether that is against single-high man or zone with the backside corner locked in coverage, quarterback Kenny Pickett can take his shots here on fade throws.

• Kansas City Chiefs QB Patrick Mahomes vs. the Los Angeles Chargers' 2-Man coverage: The Chargers have played 2-Man coverage on 17.3% of opponents' dropbacks this year, the second-highest rate in the league, and we've seen L.A. deploy this two-high look versus Mahomes in previous matchups. Here, the Chiefs can push the safeties deep while creating mid-level coverage voids for tight end Travis Kelce on over routes and in-breakers.

• For more breakdowns, check out Matt Bowen's Film Room.

Mike Clay's Eliminator Challenge advice

• Seattle Seahawks (vs. Arizona Cardinals): This is an odd week in which no team has their highest remaining win probability. The closest are the Seahawks (75%), Washington Commanders (55%) and New York Giants (45%), all of which have their second-highest odds. Especially since Washington and New York are facing each other, Seattle is the easy pick here. The 3-2 Seahawks (10th in offensive + defensive EPA) are at home against a 1-5 Cardinals squad (27th) that is still without starting QB Kyler Murray.

• Follow Clay's Eliminator Challenge advice all season long and find other tips for Week 7 here.

Al Zeidenfeld's DFS plays

• This is, on paper, the ugliest DraftKings main slate of the season to this point. But someone's going to win the money, and it may as well be us! There are a couple of Route 1 attacks we can go with to pay up for at running back with Josh Jacobs ($7,400) and Kenneth Walker III ($7,000) as well as value options like Jerome Ford ($5,100, Isiah Pacheco ($6,100) and Zach Evans ($4,000) -- or whoever ends up leading the Rams backfield this weekend against the Steelers. All of that will wrap around stacking options of the Chargers and Chiefs, if you have the salary, or the Cardinals, who project to play from behind against a Seahawks pass defense that has given up the most fantasy points to opposing receivers, if you're looking for value.

• More DFS plays here.

Seth Walder's biggest edges from ESPN Analytics

• Buffalo Bills QB Josh Allen UNDER 0.5 interceptions (+108): Allen has thrown picks in four of six games this season, but crucially only in one of Buffalo's three blowout victories. That's what we expect Sunday against the New England Patriots, and it reduces the chances of a pick. If the Bills get out to a lead, Allen can limit the risk taking.

• Tampa Bay Buccaneers LB Devin White OVER 6.5 tackles + assists (-106): White's tackle share is substantially higher against the run than the pass. And we know who loves running the ball: Arthur Smith. I project White for 7.4 tackles + assists.

David Purdum's Action Report

• We're in store for another windy Sunday, with bettors and bookmakers putting on their meteorologist hats to predict the forecast and determine its impact. Four games -- Bills at Patriots, Commanders at Giants, Detroit Lions at Ravens and Miami Dolphins at Philadelphia Eagles -- have forecasts with winds of 19 mph or stronger. The total on each game dropped during the week, most notably in the Commanders-Giants game. The total opened at 42.5 last Sunday but had dropped to 37.5 as of Thursday. Other movement: Bills-Patriots went from 43.5 on Sunday to 40 by Thursday, Lions-Ravens moved from 45 to 43 on Sunday, and Dolphins-Eagles went from 52.5 on Sunday to 51.5 Thursday. Last week, in similar windy conditions, 12 of 14 games went under the total, with one push. It was the most prolific week of unders since Week 1 of the 1996 season, when unders went 13-2. On the season, 61.5% of games have gone under the total, the highest percentage of unders through six weeks since 1991.

• The SuperBook in Las Vegas reported early sharp action on the Ravens -3 (even) vs. the Lions, Steelers -3.5 and +3 (even) at Las Vegas Raiders, and on the Minnesota Vikings +7 vs. the 49ers.

Erin Dolan's 'Dolan Out Winners'