Week 5 of the 2024 College Football season features four games between AP Top 25 ranked opponents.
The slate is led by a top-five SEC clash as No. 2 Georgia heads to Tuscaloosa to take on No. 4 Alabama in a rematch of last year's SEC Championship game (7:30 p.m. on ESPN+/ABC).
There are also some key ranked battles in both the Big Ten and Big 12 as conference title races heat up amidst the season's early College Football Playoff conversations.
Here are all the odds and lines for games with Top 25 teams on the Week 5 slate.
All odds are accurate as of timestamp. For the latest odds go to ESPN BET.
Virginia Tech at No. 7 Miami (-17)
Friday, 7:30 p.m. ET, ESPN
Records: Virginia Tech 2-2; Miami 4-0
Opening Line: Miami -16.5, O/U 56.5 (-110)
Money line: Virginia Tech (+550); Miami (-800)
Over/Under: 56.5 (O -110, U 110)
FPI Projection Miami by 20.2 points, 90% probability to win game
Kentucky at No. 6 Ole Miss (-17)
Saturday, Noon p.m. ET, ABC
Records: Kentucky 2-2; Ole Miss 4-0
Opening Line: Ole Miss -17.5, O/U 51.5 (-115)
Money line: Kentucky (+600); Ole Miss (-900)
Over/Under: 51.5 (O -115, U 105)
FPI Projection Ole Miss by 20.5 points, 90% probability to win game
Minnesota at No. 12 Michigan (-10)
Saturday, Noon p.m. ET, FOX
Records: Minnesota 2-2; Michigan 3-1
Opening Line: Michigan -10.5, O/U 39.5 (-105)
Money line: Minnesota (+360); Michigan (-450)
Over/Under: 39.5 (O -105, U 115)
FPI Projection Michigan by 11.2 points, 77% probability to win game
No. 20 Oklahoma State at No. 23 Kansas State (-5.5)
Saturday, Noon p.m. ET, ESPN
Records: Oklahoma State 3-1; Kansas State 3-1
Opening Line: Kansas State -5.5, O/U 54.5 (-110)
Money line: Oklahoma State (+180); Kansas State (-215)
Over/Under: 54.5 (O -110, U 110)
FPI Projection Oklahoma State by 1 points, 53% probability to win game
No. 22 BYU (-2.5) at Baylor
Saturday, Noon p.m. ET, FS1
Records: BYU 4-0; Baylor 2-2
Opening Line: Baylor -2.5, O/U 45.5 (-105)
Money line: BYU (+120); Baylor (-140)
Over/Under: 45.5 (O -105, U -115)
FPI Projection BYU by 0.7 points, 52% probability to win game
Wisconsin at No. 13 USC (-14.5)
Saturday, 3:30 p.m. ET, CBS
Records: Wisconsin 2-1; USC 2-1
Opening Line: USC -14.5, O/U 51.5 (-110)
Money line: Wisconsin (+475); USC (-650)
Over/Under: 51.5 (O EVEN, U -120)
FPI Projection USC by 18.2 points, 88% probability to win game
No. 15 Louisville at No. 16 Notre Dame (-4)
Saturday, 3:30 p.m. ET, Peacock
Records: Louisville 3-0; Notre Dame 3-1
Opening Line: Notre Dame -4.5, O/U 48.5 (-105)
Money line: Louisville (+170); Notre Dame (-200)
Over/Under: 48.5 (O -105, U -115)
FPI Projection Notre Dame by 6.9 points, 68% probability to win game
Arkansas at No. 24 Texas A&M -4
Saturday, 3:30 p.m. ET, ESPN
Records: Arkansas 3-1; Texas A&M 3-1
Opening Line: Texas A&M -4, O/U 52.5 (-105)
Money line: Arkansas (+155); Texas A&M (-185)
Over/Under: 52.5 (O -105, U -115)
FPI Projection Texas A&M by 2.2 points, 56% probability to win game
No. 21 Oklahoma (-2.5) at Auburn
Saturday, 3:40 PM ET, ABC
Records: Oklahoma 3-1; Auburn 2-2
Opening Line: Oklahoma -2.5, O/U 47.5 (-110)
Money line: Oklahoma (-140); Auburn (+120)
Over/Under: 47.5 (O -110, U -110)
FPI Projection Oklahoma by 2.7 points, 57% probability to win game
Mississippi State at No. 1 Texas (-38.5)
Saturday, 4:15 p.m. ET, SEC Network
Records: Mississippi State 1-3; Texas 4-0
Opening Line: Texas -38, O/U 61.5 (-105)
Money line: Mississippi State (+4000); Texas (-20000)
Over/Under: 61.5 (O -105, U -115)
FPI Projection Texas by 35.2 points, 98% probability to win game
No. 3 Ohio State (-25) at Michigan State
Saturday, 7 p.m. ET, Peacock
Records: Ohio State 3-0; Michigan State 3-1
Opening Line: Ohio State -24, O/U 50.5 (-105)
Money line: Ohio State (-3000); Michigan State (+1300)
Over/Under: 49.5 (O -105, U -115)
FPI Projection Ohio State by 23.2 points, 93% probability to win game
Stanford at No. 17 Clemson (-21.5)
Saturday, 7 p.m. ET, ESPN
Records: Stanford 2-1; Clemson 2-1
Opening Line: Clemson -22, O/U 57.5 (-110)
Money line: Stanford (+1100); Clemson (-2000)
Over/Under: 57.5 (O -110, U -110)
FPI Projection Clemson by 19.3 points, 89% probability to win game
No. 18 Iowa State (-12.5) at Houston
Saturday, 7 p.m. ET, FS1
Records: Iowa State 3-0; Houston 1-3
Opening Line: Iowa State -12.5, O/U 43.5 (-105)
Money line: Iowa State (-550); Houston (+425)
Over/Under: 43.5 (O -105, U -115)
FPI Projection Iowa State by 12.1 points, 79% probability to win game
No. 2 Georgia (-1.5) at No. 4 Alabama
Saturday, 7:30 p.m. ET, ABC, ESPN+
Records: Georgia 3-0; Alabama 3-0
Opening Line: Georgia -2.5, O/U 51.5 (-105)
Money line: Georgia (-125); Alabama (+105)
Over/Under: 49.5 (O -110, U -110)
FPI Projection Alabama by 6.1 points, 66% probability to win game
No. 19 Illinois at No. 9 Penn State (-17.5)
Saturday, 7:30 p.m. ET, NBC
Records: Illinois 4-0; Penn State 3-0
Opening Line: Penn State -17.5, O/U 47.5 (-110)
Money line: Illinois (+700); Penn State (-1000)
Over/Under: 47.5 (O -110, U -110)
FPI Projection Penn State by 16.9 points, 86% probability to win game
South Alabama at No. 14 LSU (-20.5)
Saturday, 7:45 p.m. ET, SEC Network
Records: South Alabama 2-2; LSU 3-1
Opening Line: LSU -20.5, O/U 65.5 (-105)
Money line: South Alabama (+900); LSU (-1600)
Over/Under: 65.5 (O -105, U -115)
FPI Projection LSU by 11.9 points, 78% probability to win game
Washington State at No. 25 Boise State (-7)
Saturday, 10 p.m. ET, FS1
Records: Washington State 4-0; Boise State 2-1
Opening Line: Boise State -7, O/U 64.5 (-115)
Money line: Washington State (+225); Boise State (-275)
Over/Under: 64.5 (O -115, U -105)
FPI Projection Boise State by 4.5 points, 62% probability to win game
Arizona at No. 10 Utah (-12.5)
Saturday, 10:15 p.m. ET, ESPN
Records: Arizona 2-1; Utah 4-0
Opening Line: Utah -12.5, O/U 51.5 (-110)
Money line: Arizona (+360); Utah (-450)
Over/Under: 50.5 (O -110, U -110)
FPI Projection Utah by 11.4 points, 77% probability to win game
No. 8 Oregon -24 at UCLA
Saturday, 11 p.m. ET, FOX
Records: Oregon 3-0; UCLA 1-2
Opening Line: Oregon -24, O/U 55.5 (-115)
Money line: Oregon (-2000); UCLA (+1100)
Over/Under: 55.5 (O -105, U -115)
FPI Projection Oregon by 19 points, 89% probability to win game