Taking a weekly look at Buffalo Bills running back LeSean McCoy's fantasy output last week and outlook for next week:

Week 2 statistics: 12 rushes, 9 yards; six receptions, 34 yards.

Week 2 fantasy output (ESPN standard scoring): 4.3 points (175th overall, 43rd among running backs)

Week 2 fantasy output (ESPN PPR scoring): 10.3 points (114th overall, 29th among running backs)

What happened last week at Carolina: A nightmare. Despite playing in a higher percentage of snaps (74 percent) than in Week 1 (70 percent), McCoy produced only 27 percent of the total yards he provided in the opener. His nine rushing yards were the fourth-fewest for a game in his career, and his fewest in a game in which he had more than six carries. Center Eric Wood told WGR 550 on Monday the Panthers' defense timed some blitzes well enough to stop a few of McCoy's carries, including on a 7-yard loss to end the third quarter. Even when the Panthers did not blitz, there was no room for him to run. McCoy was on the injury report Friday with wrist and groin ailments, and his wrist caused him to leave the field in pain Sunday for the second consecutive game before returning. However, he and coach Sean McDermott said after the game his health did not affect his performance.

What to expect this week vs. Denver: Despite McCoy's deserved reputation as a first-round fantasy talent, Sunday's performance served as a reminder he cannot do it all for Buffalo and there is still a low floor for his production in one of the NFL's worst offenses. McCoy's offensive line gave him little help against the Panthers. Overall, Bills running backs gained a total of zero yards before contact, the lowest single-game output for Buffalo since ESPN Stats & Information began tracking that statistic in 2006. This Sunday, there will be little reason for the Broncos to respect the Bills' wide receivers, especially with superior talent at cornerback in Chris Harris Jr. and Aqib Talib. That could allow Denver to creep their safeties closer to the line of scrimmage or use them in blitzes, exacerbating any issues Buffalo's offensive line might have against Denver's front seven.

Denver's fantasy points per game allowed to running backs this season (standard scoring): 20 points (fifth-fewest in NFL)

Denver's fantasy points per game allowed to running backs this season (PPR scoring): 31 points (seventh-fewest in NFL)